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Several agents have been shown to improve sleep induction and/or maintenance in patients with primary or comorbid insomnia. These… Expand The effects of mesulergine (100 and 200 microg/kg s.c.), SB 206553 (1 and 2.5 mg/kg i.p.), RP 62203 (2.5 and 4 mg/kg i.p.) and… Expand To study the role of 5-HT2A and 5-HT2C receptor subtypes in anxiety, the behavioral effects of drugs that either block or… Expand The dopamine D4 receptor is a potential target for novel antipsychotic drugs. Most available compounds with affinity for the… Expand The binding properties and localization of [3H]RP 62203, a novel ligand for 5-HT2 receptors, were investigated on rat brain… Expand In this study, quantitative autoradiography was used to determine the selectivity of RP 62203, a novel naphtosultam derivative… Expand 1 RP 62203 (2‐[3‐(4‐(4‐fluorophenyl)‐piperazinyl)propyl]naphto[1,8‐cd]isothiazole‐1,1‐dioxide) is a novel naphtosultam derivative… Expand RP 62203, a naphtosultam derivative, is an antagonist at the 5-hydroxytryptamine2 (HT2) receptor. The sleep pattern of rats… Expand The influence of the novel 5-hydroxytryptamine2 (5-HT2) receptor antagonist, RP 62203, on serotoninergic neurotransmission was… Expand The precise role of serotonin (5-HT) in anxiety remains unclear. We report here on the effects of RP 62203, a new 5-HT2… Expand