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RNF146 gene

Known as: Ring Finger Protein 146 Gene, IDUNA, DACTYLIDIN 
This gene plays a role in both the ubiquitination and degradation of poly-ADP-ribosylated proteins.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Protein poly(ADP-ribosyl)ation (PARylation) has a role in diverse cellular processes such as DNA repair, transcription, Wnt… Expand
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Highly Cited
2015
Highly Cited
2015
As the key effector in the Hippo pathway, YAP was identified as an oncoprotein whose expression is elevated in various human… Expand
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2014
2014
Studies have suggested a possible correlation between the newly identified E3 ubiquitin ligase ring finger protein 146 (RNF146… Expand
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Review
2014
Review
2014
Several cellular signaling pathways are regulated by ADP-ribosylation, a posttranslational modification catalyzed by members of… Expand
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Highly Cited
2012
Highly Cited
2012
Protein poly(ADP-ribosyl)ation and ubiquitination are two key post-translational modifications regulating many biological… Expand
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2012
2012
The WWE domain is often identified in proteins associated with ubiquitination or poly-ADP-ribosylation. Structural information… Expand
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Highly Cited
2011
Highly Cited
2011
The Wnt/β-catenin signalling pathway plays essential roles in embryonic development and adult tissue homeostasis, and… Expand
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Highly Cited
2011
Highly Cited
2011
Canonical Wnt signaling is controlled intracellularly by the level of β-catenin protein, which is dependent on Axin scaffolding… Expand
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Highly Cited
2011
Highly Cited
2011
Cherubism is an autosomal-dominant syndrome characterized by inflammatory destructive bony lesions resulting in symmetrical… Expand
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Highly Cited
2008
Highly Cited
2008
We performed a three-phase genome-wide association study (GWAS) using cases and controls from a genetically isolated population… Expand
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