RNF145 gene

Known as: FLJ31951, RNF145, ring finger protein 145 
 
National Institutes of Health

Related topics

Related topics

1 relation
RNF14 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
Mammalian HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the cholesterol biosynthetic pathway and the therapeutic target… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2017
2017
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP
Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs. Here, we report that RNF145, a previously… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2017
2017
Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene
Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein… (More)
Is this relevant?
2015
2015
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst
The phagocyte oxidative burst, mediated by Nox2 NADPH oxidase-derived reactive oxygen species, confers host defense against a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?