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RNF145 gene
Known as:
FLJ31951
, RNF145
, ring finger protein 145
National Institutes of Health
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Related topics
1 relation
RNF14 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase
Luyi Jiang
,
Wei Jiang
,
+7 authors
B. Song
The Journal of Biological Chemistry
2018
Corpus ID: 4912998
Cholesterol biosynthesis is tightly regulated in the cell. For example, high sterol concentrations can stimulate degradation of…
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2018
2018
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
Sam A. Menzies
,
N. Volkmar
,
+4 authors
P. Lehner
bioRxiv
2018
Corpus ID: 54632852
HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the cholesterol biosynthetic pathway and the therapeutic target of statins…
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2017
2017
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP
Li Zhang
,
P. Rajbhandari
,
+7 authors
P. Tontonoz
eLife
2017
Corpus ID: 27819937
Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs. Here, we report that RNF145, a previously…
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2017
2017
Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene
Emma C L Cook
,
Jessica K. Nelson
,
+7 authors
N. Zelcer
PloS one
2017
Corpus ID: 33333629
Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein…
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2015
2015
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst
D. Graham
,
Christine E. Becker
,
+9 authors
R. Xavier
Nature communications
2015
Corpus ID: 10771172
The phagocyte oxidative burst, mediated by Nox2 NADPH oxidase-derived reactive oxygen species, confers host defense against a…
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2009
2009
Detection of Cytogenetic Abnormalities Associated with Outcome Differences in Acute Myeloid Leukemia Using Array-Based Comparative Genomic Hybridization (aCGH) Analysis.
K. Patel
,
F. Ravandi
,
+6 authors
R. Luthra
2009
Corpus ID: 208444183
Abstract 1633 Poster Board I-659 Background The presence of abnormal cytogenetic findings at diagnosis is an independent…
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