FAQ

RNA surveillance

Known as: RNA quality control, aberrant RNA catabolic process 
The set of processes involved in identifying and degrading defective or aberrant RNAs. [GOC:dgf, GOC:krc, PMID:18644474]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
024619992018

Related topics

Related topics

1 relation

Narrower (1)

nuclear RNA surveillance

Related mentions per year

Related mentions per year

1999-2018
1990200020102020
RNA surveillance
nuclear RNA surveillance

Papers overview

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2015
2015
In plants, decapping prevents RDR6-dependent production of small interfering RNAs from endogenous mRNAs
Cytoplasmic degradation of endogenous RNAs is an integral part of RNA quality control (RQC) and often relies on the removal of… (More)
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2015
2015
A Novel Route Controlling Begomovirus Resistance by the Messenger RNA Surveillance Factor Pelota
Tomato yellow leaf curl virus (TYLCV) is a devastating disease of tomato (Solanum lycopersicum) that can be effectively… (More)
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2014
2014
The UPF1 RNA Surveillance Gene is Commonly Mutated in Pancreatic Adenosquamous Carcinoma
Pancreatic adenosquamous carcinoma (ASC) is an enigmatic and aggressive tumor that has a worse prognosis and higher metastatic… (More)
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2013
2013
R-Loop Mediated Transcription-Associated Recombination in trf4Δ Mutants Reveals New Links between RNA Surveillance and Genome Integrity
To get further insight into the factors involved in the maintenance of genome integrity we performed a screening of Saccharomyces… (More)
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2013
2013
Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants
Eukaryotic RNA quality control (RQC) uses both endonucleolytic and exonucleolytic degradation to eliminate dysfunctional RNAs. In… (More)
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2013
2013
Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.
The eukaryotic exosome exoribonuclease Rrp6 forms a complex with Rrp47 that functions in nuclear RNA quality control mechanisms… (More)
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Highly Cited
2006
Highly Cited
2006
The Human RNA Surveillance Factor UPF1 Is Required for S Phase Progression and Genome Stability
The eukaryotic nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs carrying premature stop codons (PTC). In humans, NMD… (More)
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Highly Cited
2005
Highly Cited
2005
Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity
The Ro 60 kDa autoantigen is a major target of the immune response in patients with systemic lupus erythematosus. In vertebrate… (More)
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Highly Cited
2004
Highly Cited
2004
RNA Integrity Number (RIN) – Standardization of RNA Quality Control Application
The assessment of RNA integrity is a critical first step in obtaining meaningful gene expression data. Using intact RNA is a key… (More)
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Review
1999
Review
1999
A Perfect Message RNA Surveillance and Nonsense-Mediated Decay
the disposal of nonfunctional by-products of normal The robustness of biological systems depends on the RNA processing. function… (More)
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