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RNA surveillance

Known as: RNA quality control, aberrant RNA catabolic process 
The set of processes involved in identifying and degrading defective or aberrant RNAs. [GOC:dgf, GOC:krc, PMID:18644474]
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (3)

cytoplasmic RNA surveillancemitochondrial RNA surveillancenuclear RNA surveillance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery
DNA-based antisense oligonucleotides (ASOs) elicit cleavage of the targeted RNA by the endoribonuclease RNase H1, whereas siRNAs… Expand
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Highly Cited
2014
Highly Cited
2014
The UPF1 RNA Surveillance Gene is Commonly Mutated in Pancreatic Adenosquamous Carcinoma
Pancreatic adenosquamous carcinoma (ASC) is an enigmatic and aggressive tumor that has a worse prognosis and higher metastatic… Expand
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Review
2007
Review
2007
RNA Quality Control in Eukaryotes
Eukaryotic cells contain numerous RNA quality-control systems that are important for shaping the transcriptome of eukaryotic… Expand
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Highly Cited
2006
Highly Cited
2006
The Human RNA Surveillance Factor UPF1 Is Required for S Phase Progression and Genome Stability
The eukaryotic nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs carrying premature stop codons (PTC). In humans, NMD… Expand
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Highly Cited
2005
Highly Cited
2005
A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the… Expand
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Highly Cited
2005
Highly Cited
2005
Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity
The Ro 60 kDa autoantigen is a major target of the immune response in patients with systemic lupus erythematosus. In vertebrate… Expand
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Review
2005
Review
2005
Messenger RNA Surveillance: Neutralizing Natural Nonsense
Messenger RNA transcripts that contain premature stop codons are degraded by a process termed nonsense-mediated mRNA decay (NMD… Expand
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Highly Cited
2004
Highly Cited
2004
RNA Integrity Number ( RIN ) – Standardization of RNA Quality Control Application
The assessment of RNA integrity is a critical first step in obtaining meaningful gene expression data. Using intact RNA is a key… Expand
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Review
1999
Review
1999
A Perfect Message RNA Surveillance and Nonsense-Mediated Decay
the disposal of nonfunctional by-products of normal The robustness of biological systems depends on the RNA processing. function… Expand
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Highly Cited
1999
Highly Cited
1999
Yeast Upf Proteins Required for RNA Surveillance Affect Global Expression of the Yeast Transcriptome
ABSTRACT mRNAs are monitored for errors in gene expression by RNA surveillance, in which mRNAs that cannot be fully translated… Expand
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