RNA-directed DNA polymerase activity

Known as: RNA revertase activity, reverse transcriptase activity, RNA-dependent deoxyribonucleate nucleotidyltransferase activity 
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The Bmi-1 oncoprotein regulates proliferation and oncogenesis in human cells. Its overexpression leads to senescence bypass in… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2006
2006
DNA polymerases enable key technologies in modern biology but for many applications, native polymerases are limited by their… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
LINE-1 retrotransposons (L1s) constitute ∼17% of human DNA, and their activity continues to affect genome evolution… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Aging is associated with a rise in intracellular reactive oxygen species (ROS) and a loss of telomerase reverse transcriptase… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The Nef protein of human immunodeficiency virus type 1 (HIV-1) stimulates viral infectivity. The mechanism of this phenotype was… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Hepatitis B viruses (hepadnaviruses) replicate their DNA genomes by reverse transcription of an RNA intermediate. Efforts to… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
A T cell clone (ACH-2) derived from T cells infected with HIV-1 was found to produce HIV-1 in response to stimulation with a… (More)
Is this relevant?
Highly Cited
1988
Highly Cited
1988
Monocytes were maintained in tissue culture for greater than 3 mo in media supplemented with rCSF-1. These cultures provided… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1988
Highly Cited
1988
Myeloid progenitor cells were highly purified from normal human bone marrow by positive immunoselection with high-affinity… (More)
Is this relevant?
Highly Cited
1982
Highly Cited
1982
A retrovirus (ATLV) was unequivocally demonstrated in human adult T-cell leukemia (ATL) cell lines by density (1.152-1.155 g/cm3… (More)
Is this relevant?