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RNA Polymerase II

Known as: RNA Pol II, DNA Dependent RNA Polymerase II, Pol II 
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Mediator is an essential, large, multisubunit, transcriptional co-activator highly conserved across eukaryotes. Mediator… Expand
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Highly Cited
2011
Highly Cited
2011
Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is… Expand
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Highly Cited
2007
Highly Cited
2007
Histone modifications are implicated in influencing gene expression. We have generated high-resolution maps for the genome-wide… Expand
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Highly Cited
2005
Highly Cited
2005
Brd4 is a mammalian bromodomain protein that binds to acetylated chromatin. Proteomic analysis revealed that Brd4 interacts with… Expand
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Review
2004
Review
2004
Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP II) have identified this stage as a… Expand
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Highly Cited
2003
Highly Cited
2003
Changes in promoter structure and occupation have been shown to modify the splicing pattern of several genes, evidencing a… Expand
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Highly Cited
2001
Highly Cited
2001
The crystal structure of RNA polymerase II in the act of transcription was determined at 3.3 A resolution. Duplex DNA is seen… Expand
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Highly Cited
1999
Highly Cited
1999
DRB is a classic inhibitor of transcription elongation by RNA polymerase II (pol II). Since DRB generally affects class II genes… Expand
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Review
1996
Review
1996
Transcription initiation on protein-encoding genes represents a major control point for gene expression in eukaryotes, and is… Expand
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Highly Cited
1990
Highly Cited
1990
Optimized weight matrices defining four major eukaryotic promoter elements, the TATA-box, cap signal, CCAAT-, and GC-box, are… Expand
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