RNA-Binding Protein EWS

Known as: EWS Protein, EWS Proto Oncogene Protein, Proto-Oncogene Protein, EWS 
A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result in the formation of fusion proteins containing… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find… (More)
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Highly Cited
2009
Highly Cited
2009
The fusion between EWS and ETS family members is a key oncogenic event in Ewing tumors and important EWS-FLI1 target genes have… (More)
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Highly Cited
2009
Highly Cited
2009
Ewing sarcoma family of tumors (ESFT) is an undifferentiated neoplasm of the bone and soft tissue. ESFT is characterized by a… (More)
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2006
2006
RNA helicase A (RHA), a member of the DEXH box helicase family of proteins, is an integral component of protein complexes that… (More)
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2001
2001
The chimeric gene EWS/FLI is present in at least 85% of Ewing's sarcomas as a result of chromosomal translocations. The resulting… (More)
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Highly Cited
1998
Highly Cited
1998
As a result of the t(11;22)(q24;q12) chromosomal translocation characterizing the Ewing family of tumors (ET), the amino terminal… (More)
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Highly Cited
1998
Highly Cited
1998
PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1 genes, due to the t(11;22)(q24;q12… (More)
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Highly Cited
1994
Highly Cited
1994
The 5' half of the EWS gene has recently been described to be fused to the 3' regions of genes encoding the DNA-binding domain of… (More)
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Highly Cited
1993
Highly Cited
1993
EWS/FLI-1 is a chimeric protein formed by a tumor-specific 11;22 translocation found in both Ewing's sarcoma and primitive… (More)
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Highly Cited
1993
Highly Cited
1993
The 11;22 chromosomal translocation specifically linked to Ewing sarcoma and primitive neuroectodermal tumor results in a… (More)
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