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RNA-Binding Protein EWS

Known as: EWS Protein, EWS Proto Oncogene Protein, Proto-Oncogene Protein, EWS 
A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result in the formation of fusion proteins containing… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find… Expand
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Highly Cited
2012
Highly Cited
2012
Ewing's sarcoma family of tumors (ESFT) refers to aggressive malignancies which frequently harbor characteristic EWS-FLI1 or EWS… Expand
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Highly Cited
2009
Highly Cited
2009
Many sarcomas and leukemias carry nonrandom chromosomal translocations encoding tumor-specific mutant fusion transcription… Expand
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Highly Cited
2006
Highly Cited
2006
RNA helicase A (RHA), a member of the DEXH box helicase family of proteins, is an integral component of protein complexes that… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1 genes, due to the t(11;22)(q24;q12… Expand
Highly Cited
1998
Highly Cited
1998
As a result of the t(11;22)(q24;q12) chromosomal translocation characterizing the Ewing family of tumors (ET), the amino terminal… Expand
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Highly Cited
1994
Highly Cited
1994
The 5' half of the EWS gene has recently been described to be fused to the 3' regions of genes encoding the DNA-binding domain of… Expand
Highly Cited
1994
Highly Cited
1994
Although recent data have demonstrated that the chimeric EWS-FLI-1 cDNA isolated from cases of Ewing's sarcoma can transform NIH… Expand
Highly Cited
1993
Highly Cited
1993
EWS/FLI-1 is a chimeric protein formed by a tumor-specific 11;22 translocation found in both Ewing's sarcoma and primitive… Expand
Highly Cited
1993
Highly Cited
1993
The 11;22 chromosomal translocation specifically linked to Ewing sarcoma and primitive neuroectodermal tumor results in a… Expand