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RNA-Binding Protein EWS

Known as: EWS Protein, EWS Proto Oncogene Protein, Proto-Oncogene Protein, EWS 
A ubiquitous hnRNP protein found in the CELL NUCLEUS and the CYTOPLASM. Translocations that result in the formation of fusion proteins containing… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Ewing sarcoma is a pediatric bone tumor characterized in 85% of cases by the fusion between EWS and FLI1 genes that results in… 
Highly Cited
2012
Highly Cited
2012
Ewing's sarcoma family of tumors (ESFT) refers to aggressive malignancies which frequently harbor characteristic EWS-FLI1 or EWS… 
Highly Cited
2011
Highly Cited
2011
BACKGROUND Chromosomal translocations generating oncogenic transcription factors are the hallmark of a variety of tumors… 
Highly Cited
2009
Highly Cited
2009
Many sarcomas and leukemias carry nonrandom chromosomal translocations encoding tumor-specific mutant fusion transcription… 
Highly Cited
1998
Highly Cited
1998
PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1 genes, due to the t(11;22)(q24;q12… 
Highly Cited
1994
Highly Cited
1994
The 5' half of the EWS gene has recently been described to be fused to the 3' regions of genes encoding the DNA-binding domain of… 
Highly Cited
1994
Highly Cited
1994
Although recent data have demonstrated that the chimeric EWS-FLI-1 cDNA isolated from cases of Ewing's sarcoma can transform NIH… 
Highly Cited
1993
Highly Cited
1993
EWS/FLI-1 is a chimeric protein formed by a tumor-specific 11;22 translocation found in both Ewing's sarcoma and primitive… 
Highly Cited
1993
Highly Cited
1993
The 11;22 chromosomal translocation specifically linked to Ewing sarcoma and primitive neuroectodermal tumor results in a…