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RIOK3 gene

Known as: SUDD, RIO kinase 3, SUDD, ASPERGILLUS NIDULANS, HOMOLOG OF 
 
National Institutes of Health

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Related topics

1 relation
RIOK2 gene

Papers overview

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2018
2018
The atypical protein kinase RIOK3 contributes to glioma cell proliferation/survival, migration/invasion and the AKT/mTOR signaling pathway.
The RIO (right open reading frame) protein kinases include RIOK1, RIOK2 and RIOK3. Emerging evidence has suggested an important… Expand
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2018
2018
Clinical and symptom scores are significantly correlated with fecal microbiota features in patients with symptomatic uncomplicated diverticular disease: a pilot study
Background There is growing consensus that symptomatic uncomplicated diverticular disease is a chronic inflammatory condition… Expand
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2015
2015
RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.
MDA5 is a cytoplasmic viral double-stranded RNA (dsRNA) sensor and triggers type I interferon (IFN) production. MDA5 assembles… Expand
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2014
2014
1052 Daily Mesalamine Fails to Prevent Recurrent Diverticulitis in a Large Placebo Controlled Multicenter Trial
3 focus groups of 45 SUDD patients and an expert panel of five gastroenterologists and surgeons. We developed the DV-QOL items… Expand
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2014
2014
RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production.
Detection of cytosolic nucleic acids by pattern recognition receptors leads to the induction of type I interferons (IFNs) and… Expand
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2013
2013
RIO kinase 3 acts as a SUFU-dependent positive regulator of Hedgehog signaling.
Suppressor of fused (SUFU) is an essential negative regulator of the mammalian Hedgehog (HH) signaling pathway and its loss is… Expand
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2012
2012
Human RioK3 is a novel component of cytoplasmic pre-40S pre-ribosomal particles
Maturation of the 40S ribosomal subunit precursors in mammals mobilizes several non-ribosomal proteins, including the atypical… Expand
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2010
2010
Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells.
Promoter DNA methylation of CpG islands is an important epigenetic mechanism in cancer development. We have characterized the… Expand
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2009
2009
RIOK3 interacts with caspase-10 and negatively regulates the NF-κB signaling pathway
RIOK3 was initially characterized as a homolog of Aspergillus nidulans sudD and showed down-regulation at the invasive front of… Expand
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2009
2009
Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung
BackgroundPancreatic cancer is still associated with devastating prognosis. Real progress in treatment options has still not been… Expand
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