RHOC gene

Known as: ARH9, APLYSIA RAS-RELATED HOMOLOG 9, RhoC 
This gene plays a role in signal transduction. It is involved in several cellular functions including cytoskeletal remodeling and cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Several studies suggest that RhoA and RhoC, despite their sequence similarity, have different roles in cell migration and… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNAs (miRNAs) are effective post-transcriptional regulators of gene expression and are important in many biological… (More)
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Highly Cited
2005
Highly Cited
2005
The Rho proteins are Ras-related guanosine triphosphatases (GTPases) that function in cytoskeletal reorganization, cell migration… (More)
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Highly Cited
2005
Highly Cited
2005
Overexpression of RhoA or RhoC in breast cancer indicates a poor prognosis, due to increased tumor cell proliferation and… (More)
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Review
2004
Review
2004
Higher vertebrates have 3 Rho GTPases, RhoA, RhoB, and RhoC, which share 85% amino acid sequence identity. Here, we compare and… (More)
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Highly Cited
2004
Highly Cited
2004
Hepatocellular carcinoma (HCC) is one of the most malignant human tumours because of its high incidence of metastasis. The… (More)
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Highly Cited
2003
Highly Cited
2003
To clarify the role of small GTPases Rho in the biologic behavior of ovarian carcinoma, we first examined the mRNA expression of… (More)
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Highly Cited
2000
Highly Cited
2000
The most damaging change during cancer progression is the switch from a locally growing tumour to a metastatic killer. This… (More)
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Highly Cited
2000
Highly Cited
2000
Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer and is phenotypically distinct from other forms of… (More)
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Highly Cited
1989
Highly Cited
1989
Clostridium botulinum C3 is a recently discovered exoenzyme that ADP-ribosylates a eukaryotic GTP-binding protein of the ras… (More)
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