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RET/PTC Rearrangement
Known as:
RET Gene Rearrangement
A gene rearrangement involving the RET proto-oncogene. RET gene rearrangements are associated with several different neoplastic conditions.
National Institutes of Health
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Related topics
Related topics
15 relations
Columnar Cell Variant Thyroid Gland Papillary Carcinoma
Cribriform-Morular Variant Thyroid Gland Papillary Carcinoma
Encapsulated Follicular Variant Thyroid Gland Papillary Carcinoma
Follicular Variant Thyroid Gland Papillary Carcinoma
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Concomitant RAS, RET/PTC, or BRAF mutations in advanced stage of papillary thyroid carcinoma.
M. Zou
,
E. Baitei
,
+5 authors
Yufei Shi
Thyroid
2014
Corpus ID: 12231119
BACKGROUND RET/PTC rearrangement, RAS, and BRAF mutations are considered to be mutually exclusive in papillary thyroid carcinoma…
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Highly Cited
2009
Highly Cited
2009
High Rate of BRAF and RET/PTC Dual Mutations Associated with Recurrent Papillary Thyroid Carcinoma
Y. Henderson
,
T. Shellenberger
,
+4 authors
G. Clayman
Clinical Cancer Research
2009
Corpus ID: 81113
Purpose: Papillary thyroid carcinoma (PTC), the most common thyroid malignancy, usually possesses BRAF mutation or rearranged in…
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Highly Cited
2008
Highly Cited
2008
Sorafenib Potently Inhibits Papillary Thyroid Carcinomas Harboring RET/PTC1 Rearrangement
Y. Henderson
,
Soon-Hyun Ahn
,
Ya'an Kang
,
G. Clayman
Clinical Cancer Research
2008
Corpus ID: 7879959
Purpose: Papillary thyroid carcinomas (PTC) are the most common type of thyroid malignancy with one of the two mutations, RET/PTC…
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Highly Cited
2007
Highly Cited
2007
Fine-needle aspiration molecular analysis for the diagnosis of papillary thyroid carcinoma through BRAF V600E mutation and RET/PTC rearrangement.
G. Pizzolanti
,
L. Russo
,
+18 authors
C. Giordano
Thyroid
2007
Corpus ID: 25230625
OBJECTIVE To evaluate BRAF(V600E) mutation on consecutive fine-needle aspiration biopsy (FNAB) specimens in order to assess FNAB…
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Highly Cited
2005
Highly Cited
2005
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis
T. Giordano
,
R. Kuick
,
+13 authors
Y. Nikiforov
Oncogene
2005
Corpus ID: 35467920
Thyroid cancer poses a significant clinical challenge, and our understanding of its pathogenesis is incomplete. To gain insight…
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Highly Cited
2004
Highly Cited
2004
Early Occurrence of RASSF1A Hypermethylation and Its Mutual Exclusion with BRAF Mutation in Thyroid Tumorigenesis
M. Xing
,
Y. Cohen
,
+4 authors
D. Sidransky
Cancer Research
2004
Corpus ID: 15266195
Follicular epithelial cell-derived thyroid tumors are common neoplasms comprised mainly of benign thyroid adenomas, follicular…
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Highly Cited
2003
Highly Cited
2003
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC
P. Soares
,
V. Trovisco
,
+7 authors
M. Sobrinho-Simões
Oncogene
2003
Corpus ID: 19330336
Rearrangement of RET proto-oncogene is the major event in the etiopathogenesis of papillary thyroid carcinoma (PTC). We report a…
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Review
2002
Review
2002
RET/PTC rearrangement in thyroid tumors
Y. Nikiforov
Endocrine pathology
2002
Corpus ID: 23964165
Rearrangement of the RET gene, also known as RET/PTC rearrangement, is the most common genetic alteration identified to date in…
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Highly Cited
2002
Highly Cited
2002
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma.
F. Basolo
,
R. Giannini
,
+11 authors
M. Santoro
American Journal of Pathology
2002
Corpus ID: 24436678
Highly Cited
2001
Highly Cited
2001
RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults.
R. Elisei
,
C. Romei
,
+8 authors
F. Pacini
Journal of Clinical Endocrinology and Metabolism
2001
Corpus ID: 17720485
Rearrangements of the RET proto-oncogene may occur in both naturally occurring and radiation-induced papillary thyroid carcinomas…
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