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RELN protein, human

Known as: EC 3.4.21.-, Reelin, reelin protein, human 
Reelin (3460 aa, ~388 kDa) is encoded by the human RELN gene. This protein is involved in both neuronal development and proteolysis.
National Institutes of Health

Related topics

Related topics

19 relations
Binding ProteinsCerebellumEnzyme GeneExtracellular Matrix

Broader (1)

reelin protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Reelin promoter hypermethylation in schizophrenia.
Reelin mRNA and protein levels are reduced by approximately 50% in various cortical structures of postmortem brain from patients… 
Highly Cited
2005
Highly Cited
2005
Modulation of Synaptic Plasticity and Memory by Reelin Involves Differential Splicing of the Lipoprotein Receptor Apoer2
Highly Cited
2002
Highly Cited
2002
Reelin and ApoE Receptors Cooperate to Enhance Hippocampal Synaptic Plasticity and Learning*
Two apolipoprotein E (apoE) receptors, the very low density lipoprotein (VLDL) receptor and apoE receptor 2 (apoER2), are also… 
Review
2001
Review
2001
Role of the reelin signaling pathway in central nervous system development.
The neurological mutant mouse reeler has played a critical role in the evolution of our understanding of normal brain development… 
Highly Cited
2000
Highly Cited
2000
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study.
BACKGROUND Reelin (RELN) is a glycoprotein secreted preferentially by cortical gamma-aminobutyric acid-ergic (GABAergic… 
Highly Cited
2000
Highly Cited
2000
Reelin Binds α3β1 Integrin and Inhibits Neuronal Migration
Highly Cited
1999
Highly Cited
1999
Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation
Highly Cited
1999
Highly Cited
1999
Reelin Is a Ligand for Lipoprotein Receptors
Highly Cited
1998
Highly Cited
1998
Regional and Cellular Patterns of reelin mRNA Expression in the Forebrain of the Developing and Adult Mouse
The reelin gene encodes an extracellular protein that is crucial for neuronal migration in laminated brain regions. To gain… 
Highly Cited
1997
Highly Cited
1997
Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody
The neurological mouse mutant strain reeler displays abnormal laminar organization of several brain structures as a consequence… 
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