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RECQL protein, human

Known as: DNA helicase Q1-like, human, RECQ1 protein, human, RECQL 
ATP-dependent DNA helicase Q1 (649 aa, ~73 kDa) is encoded by the human RECQL gene. This protein plays a role in DNA renaturation.
National Institutes of Health

Papers overview

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2016
2016
Recently, RECQL was reported as a new breast cancer susceptibility gene. RECQL belongs to the RECQ DNA helicase family which… Expand
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Highly Cited
2015
Highly Cited
2015
Several moderate- and high-risk breast cancer susceptibility genes have been discovered, but more are likely to exist. To… Expand
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2015
2015
The genetic cause for approximately 80% of familial breast cancer patients is unknown. Here, by sequencing the entire exomes of… Expand
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Highly Cited
2013
Highly Cited
2013
Topoisomerase I (TOP1) inhibitors are an important class of anticancer drugs. The cytotoxicity of TOP1 inhibitors can be… Expand
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Highly Cited
2007
Highly Cited
2007
Background DNA helicases are ubiquitous enzymes that unwind DNA in an ATP-dependent and directionally specific manner. Unwinding… Expand
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Highly Cited
2007
Highly Cited
2007
The mouse gene Recql is a member of the RecQ subfamily of DEx-H-containing DNA helicases. Five members of this family have been… Expand
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Highly Cited
2003
Highly Cited
2003
The RECQL4 helicase gene is a member of the RECQL gene family, mutated in some Rothmund-Thomson syndrome (RTS) patients. Other… Expand
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Highly Cited
1999
Highly Cited
1999
Rothmund-Thomson syndrome (RTS; also known as poikiloderma congenitale) is a rare, autosomal recessive genetic disorder… Expand
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1999
1999
 
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Highly Cited
1994
Highly Cited
1994
A potential human DNA helicase, RECQL, was partially purified from HeLa cells, and a cDNA encoding this protein was subsequently… Expand
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