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RASSF5 wt Allele

Known as: NORE1, RAPL, RASSF3 
Human RASSF5 wild-type allele is located in the vicinity of 1q32.1 and is approximately 82 kb in length. This allele, which encodes RAS association… Expand
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Aberrant DNA methylation is a common phenomenon in human cancer. The aims of this study were to investigate the methylation… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND/AIMS The success of sorafenib in the treatment of advanced hepatocellular carcinoma (HCC) has focused interest on the… Expand
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Highly Cited
2009
Highly Cited
2009
Ras-associated protein 1 (Rap1), a small GTPase, attracted attention because of its involvement in several aspects of cell… Expand
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Highly Cited
2009
Highly Cited
2009
NORE1A (RASSF5) is a proapoptotic Ras effector that is frequently inactivated by promoter methylation in human tumors. It is… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Although the natural history and pathologic characteristics of human hepatocellular carcinoma (HCC) are well… Expand
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Highly Cited
2006
Highly Cited
2006
Rapamycin, FK506, and FK520 are immunosuppressant macrolactone natural products comprised of predominantly polyketide-based core… Expand
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Review
2005
Review
2005
Loss of heterozygosity of the small arm of chromosome 3 is one of the most common alterations in human cancer. Most notably, a… Expand
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Highly Cited
2004
Highly Cited
2004
MST1 (mammalian Sterile20-like 1) and MST2 are closely related Class II GC (protein Ser/Thr) kinases that initiate apoptosis when… Expand
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Highly Cited
2003
Highly Cited
2003
The small GTPase Rap1 is a potent activator of leukocyte integrin. However, the regulatory mechanism involved is unknown. Here… Expand
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Highly Cited
2003
Highly Cited
2003
By positional cloning, we identified two breakpoint-spanning genes in a familial clear cell renal cell carcinoma (CCRCC… Expand
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