RASSF1 wt Allele

Known as: REH3P21, Ras Association (RalGDS/AF-6) Domain Family 1 wt Allele, RDA32 
Human RASSF1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 11 kb in length. This allele, which encodes ras association… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
RASSF1A is a tumor suppressor gene that is epigenetically silenced in a wide variety of sporadic human malignancies. Expression… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We recently demonstrated that the promoter of the RASSF1A gene is hypermethylated in the placenta and hypomethylated… (More)
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Highly Cited
2006
Highly Cited
2006
DNA CpG methylation can cooperate with histone H3 lysine 9 (H3-K9) methylation in heterochromatin formation and gene silencing… (More)
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Highly Cited
2003
Highly Cited
2003
To determine the methylation profile of multiple tumor-related genes during multistep hepatocarcinogenesis, we investigated the… (More)
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Highly Cited
2002
Highly Cited
2002
The RASSF1A locus at 3p21.3 is epigenetically inactivated at high frequency in a variety of solid tumors. Expression of RASSF1A… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE We investigated the aberrant methylation profile of prostate cancers and correlated the data with clinical findings… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The recently identified RASSF1 locus is located within a 120-kilobase region of chromosome 3p21.3 that frequently… (More)
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Highly Cited
2001
Highly Cited
2001
Previously we analysed overlapping homozygous deletions in lung and breast tumours/tumour lines and defined a small region of 120… (More)
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Highly Cited
2001
Highly Cited
2001
We investigated the aberrant promoter methylation profile of bladder cancers and correlated the data with clinicopathological… (More)
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Highly Cited
2001
Highly Cited
2001
Clear cell-type renal cell carcinomas (clear RCC) are characterized almost universally by loss of heterozygosity on chromosome 3p… (More)
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