RASSF1 gene

Known as: NORE2A, Ras association domain family member 1, RASSF1A 
This gene plays a role in the maintenance of genomic integrity and possibly tumor suppression.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND/AIMS The success of sorafenib in the treatment of advanced hepatocellular carcinoma (HCC) has focused interest on the… (More)
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Highly Cited
2007
Highly Cited
2007
UNLABELLED Glycine N-methyltransferase (GNMT) is the main enzyme responsible for catabolism of excess hepatic S… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Genetic alterations were previously identified in normal epithelia adjacent to invasive cancers. The aim of this study… (More)
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Highly Cited
2006
Highly Cited
2006
Genetic and epigenetic alterations are considered to play important roles in lung cancer. Recent studies showed that EGFR and K… (More)
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Review
2005
Review
2005
Loss of heterozygosity of a segment at 3p21.3 is frequently observed in lung cancer and several other carcinomas. We have… (More)
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Highly Cited
2003
Highly Cited
2003
The Ras GTPases are a superfamily of molecular switches that regulate cellular proliferation and apoptosis in response to extra… (More)
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Highly Cited
2002
Highly Cited
2002
Recently, we have cloned and characterized the Ras association domain family 1A gene (RASSF1A) at 3p21.3, from which loss of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The recently identified RASSF1 locus is located within a 120-kilobase region of chromosome 3p21.3 that frequently… (More)
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Highly Cited
2001
Highly Cited
2001
Renal cell carcinoma (RCC), the most common adult kidney neoplasm, is histopathologically heterogeneous, with most sporadic RCCs… (More)
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Highly Cited
2000
Highly Cited
2000
Allelic loss at the short arm of chromosome 3 is one of the most common and earliest events in the pathogenesis of lung cancer… (More)
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