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RASSF1 gene

Known as: NORE2A, Ras association domain family member 1, RASSF1A 
This gene plays a role in the maintenance of genomic integrity and possibly tumor suppression.
National Institutes of Health

Related topics

Related topics

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Cell Proliferation Regulatory ProcessDNA RepairHomo sapiensNeoplastic Cell Transformation

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RASSF1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Dual-functionality of RASSF1A overexpression in A375 cells is mediated by activation of IL-6/STAT3 regulatory loop
The RASSF1A, a microtubule associated protein, is a well-known tumor suppressor silenced in various cancer via promoter… 
2016
2016
Promoter methylation and expression of RASSF 1 A genes as predictors of disease progression in colorectal cancer
Aberrant DNA methylation of RAS-association domain family (RASSF) is believed to be involved in gene inactivation process in… 
2015
2015
Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients
Dietary methyl group donors could influence the hypermethylation status of certain putative genes. The present study explored the… 
2015
2015
[The Role of 5-Aza-CdR on Methylation of Promoter in RASSF1A Gene in Endometrial Carcinoma].
OBJECTIVE To explore the effect of demethylating drug 5-Aza-2'-deoxycytidine (5-Aza-CdR) on methtylation status of the Ras… 
2014
2014
Association of RASSF 1 A Promoter Methylation with Lung Cancer Risk : a Meta-analysis
Lung cancer is the most frequent cancer worldwide still. There were more than 1.8 million new cases (13% of total cancer… 
2011
2011
Erratum to: Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors
2008
2008
Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis
To investigate the diagnostic potential of DNA methylation-based markers in tissuesamples of DCIS, we examined the prevalence and… 
2005
2005
Transcriptional Regulation of Cyclin A 2 by RASSF 1 A through the Enhanced Binding of p 120 E 4 F to the Cyclin A 2 Promoter
Recent advances in the study of RASSF1A , the candidate tumor suppressor gene, indicate a possible role of RASSF1A in cell cycle… 
2004
2004
Identification of the E 1 A-Regulated Transcription Factor p 120 E 4 F as an Interacting Partner of the RASSF 1 A Candidate Tumor Suppressor Gene
Epigenetic inactivation of the candidate tumor suppressor gene RASSF1A is a frequent and critical event in the pathogenesis of… 
2003
2003
Expression of RASSF1A gene in nasopharyngeal carcinoma.
OBJECTIVE To investigate the role of RASSF1A gene in the pathogenesis of nasopharyngeal carcinoma (NPC). METHODS RASSF1A gene… 
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