RASGRP1 wt Allele

Known as: RASGRP, hRasGRP1, MGC129998 
Human RASGRP1 wild-type allele is located in the vicinity of 15q14 and is approximately 77 kb in length. This allele, which encodes RAS guanyl… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
051019972018

Papers overview

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2011
2011
Rolling leukocytes are exposed to different adhesion molecules and chemokines. Neutrophils rolling on E-selectin induce integrin… (More)
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2009
2009
Leukocyte adhesion deficiency (LAD)-III is associated with homozygous stop codon mutations in Kindlin-3, the hematopoietic member… (More)
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Highly Cited
2007
Highly Cited
2007
Single gene mutations in beta integrins can account for functional defects of individual cells of the hematopoietic system. In… (More)
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2005
Highly Cited
2005
The RasGRPs are a family of Ras activators that possess diacylglycerol-binding C1 domains. In T cells, RasGRP1 links TCR… (More)
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2004
2004
The small GTPase, Rap1, is a potent activator of leukocyte integrins and enhances the adhesive activity of lymphocyte function… (More)
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2002
2002
T cell development in the thymus and activation of mature T cells in the periphery depend on signals stimulated by engagement of… (More)
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Highly Cited
2000
Highly Cited
2000
The Ras signaling pathway plays a critical role in thymopoiesis and T cell activation, but the mechanism of Ras regulation is… (More)
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Highly Cited
2000
Highly Cited
2000
Stimulation of the T-cell receptor (TCR) alters a number of intracellular signaling pathways including one that involves protein… (More)
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Highly Cited
1998
Highly Cited
1998
RasGRP, a guanyl nucleotide-releasing protein for the small guanosine triphosphatase Ras, was characterized. Besides the… (More)
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Highly Cited
1998
Highly Cited
1998
Ras proteins, key regulators of growth, differentiation, and malignant transformation, recently have been implicated in synaptic… (More)
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