FAQ

RASD2 gene

Known as: TUMOR ENDOTHELIAL MARKER 2, MGC:4834, Rhes 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2016
024619872016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Reinstating Aberrant mTORC1 Activity in Huntington’s Disease Mice Improves Disease Phenotypes
Huntington's disease (HD) is caused by a polyglutamine tract expansion in huntingtin (HTT). Despite HTTs ubiquitous expression… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
Rhes deletion is neuroprotective in the 3-nitropropionic acid model of Huntington's disease.
Although the mutated protein causing Huntington's disease (HD) is expressed throughout the body, the major pathology of HD is… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
2010
2010
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
We recently reported that the small G-protein Rhes has the properties of a SUMO-E3 ligase and mediates mutant huntingtin (mHtt… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.
Huntington's disease (HD) is caused by a polyglutamine repeat in the protein huntingtin (Htt) with mutant Htt (mHtt) expressed… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.
Rhes is a small GTP-binding protein prominently localized in the striatum. Previous findings obtained in cell culture systems… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Rhes, the Ras homolog enriched in striatum, is reduced under conditions of dopamine supersensitivity.
Striatal dopamine receptors become supersensitive when dopaminergic input is removed through either surgical denervation or… (More)
Is this relevant?
2004
2004
Rhes is involved in striatal function.
The development and the function of central nervous system depend on thyroid hormones. In humans, the lack of thyroid hormones… (More)
Is this relevant?
2004
2004
The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors
The Ras homolog enriched in striatum, Rhes, is the product of a thyroid hormone-regulated gene during brain development. Rhes and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2001
2001
Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum.
Thyroid hormone action on brain development is essentially exerted through regulation of the expression rate of a number of genes… (More)
Is this relevant?
1999
1999
Rhes: A striatal-specific Ras homolog related to Dexras1.
We have characterized an apparently full-length cDNA corresponding to a rat mRNA, SE6C, previously identified by subtractive… (More)
Is this relevant?