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RARA gene

Known as: NR1B1, RAR, ALPHA FORM, RETINOIC ACID RECEPTOR, ALPHA 
This gene plays a role in transcription and retinoic acid receptor signal transduction.
National Institutes of Health

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Related topics

28 relations
Acute Promyelocytic LeukemiaBiologic DevelopmentCell Differentiation processCell Proliferation

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RARA wt Allele

Papers overview

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2009
2009
p38 Mitogen‐activated protein kinase‐dependent regulation of SRC‐3 and involvement in retinoic acid receptor α signaling in embryonic cortical neurons
Appropriate retinoic acid (RA) signaling is essential in the development of the central nervous system (CNS). Previous studies… 
2003
2003
Overexpression of dominant negative retinoic acid receptor alpha causes alveolar abnormality in transgenic neonatal lungs.
To assess retinoic acid receptor (RAR) function in alveolarization and respiratory epithelial cell differentiation/proliferation… 
2001
2001
The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical…
Monocyte differentiation induced by 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) is interrupted during the course of acute… 
Review
2001
Review
2001
Modeling acute promyelocytic leukemia in the mouse: new insights in the pathogenesis of human leukemias.
Acute promyelocytic leukemia (APL) is characterized by the expansion of malignant myeloid cells blocked at the promyelocytic… 
1998
1998
Retinoic acid down-regulates the expression of the vasoactive intestinal polypeptide receptor type-1 in human breast carcinoma cell lines.
Four breast carcinoma cell lines (T47D, ZR-75-1, MDA-MB-231, and MCF-7) were tested for regulation of the expression of… 
1997
1997
Male infertility caused by epididymal dysfunction in transgenic mice expressing a dominant negative mutation of retinoic acid receptor alpha 1.
Retinoids are thought to be required for the normal development and maturation of a number of tissues, including most epithelia… 
1993
1993
Antimutagenesis and Anticarcinogenesis Mechanisms III
Luigi M. De Luca National Cancer Center Institute Bethesda, Maryland 20892 USA It has become evident that retinoids control… 
1993
1993
Co-amplification of erbB2, topoisomerase II alpha and retinoic acid receptor alpha genes in breast cancer and allelic loss at topoisomerase I on chromosome 20.
The DNA topoisomerase enzymes are targets for the cytotoxic effects of a number of anticancer agents termed topoisomerase… 
Review
1992
Review
1992
RARA and PML genes in acute promyelocytic leukemia.
Acute promyelocytic leukemia (APL) is characterized by a specific chromosome translocation t(15;17). Recently, using molecular… 
Highly Cited
1989
Highly Cited
1989
Expression of retinoic acid receptor alpha mRNA in human leukemia cells.
The expression of the newly described human retinoic acid receptor alpha (RAR alpha) in six nonlymphoid and six lymphoid leukemia… 
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