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RAR and RXR Degradation Pathway
Degradation of the RAR and RXR by the proteasome
Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome…
National Institutes of Health
RARA wt Allele
RXRA wt Allele
Retinoic Acid Receptor Alpha, human
Retinoic Acid Receptor RXR-Alpha
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1 alpha,25-dihydroxyvitamin D3 transrepresses retinoic acid transcriptional activity via vitamin D receptor in myeloid cells.
Corpus ID: 39173208
Granulocytes and monocytes originate from a common committed progenitor cell. Commitment to either granulocytic or monocytic…
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