RAD18 protein, human

Known as: Postreplication Repair Protein RAD18, RING Finger Protein 73, hRAD18 protein, human 
E3 ubiquitin-protein ligase RAD18 (495 aa, ~56 kDa) is encoded by the human RAD18 gene. This protein plays a role in both ubiquitination and… (More)
National Institutes of Health

Papers overview

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2011
2011
In ubiquitin conjugation, different combinations of E2 and E3 enzymes catalyse either monoubiquitination or ubiquitin chain… (More)
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2011
2011
Camptothecin (CPT) and related chemotherapeutic drugs induce formation of DNA Topoisomerase I (Top1) covalent or cleavage… (More)
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2010
2010
The Fanconi anemia (FA) network is important for the repair of interstrand DNA cross-links. A key event in FA pathway activation… (More)
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Highly Cited
2009
Highly Cited
2009
To maintain genome stability, cells respond to DNA damage by activating signalling pathways that govern cell-cycle checkpoints… (More)
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2006
2006
We have investigated mechanisms that recruit the translesion synthesis (TLS) DNA polymerase Polkappa to stalled replication forks… (More)
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2004
2004
Ubiquitination of proteins was previously shown to modulate various processes of DNA metabolism. PCNA, a processivity factor with… (More)
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2003
2003
In lower eukaryotes, Rad18 plays a crucial role in postreplication repair. Previously, we isolated a human homologue of RAD18… (More)
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2000
2000
Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. The yeast Saccharomyces… (More)
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1997
1997
The RAD6 gene of Saccharomyces cerevisiae encodes a ubiquitin-conjugating enzyme required for postreplicational repair of UV… (More)
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Highly Cited
1994
Highly Cited
1994
The RAD6 gene of Saccharomyces cerevisiae encodes a ubiquitin-conjugating enzyme that is required for postreplication repair of… (More)
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