FAQ

RABIF gene

Known as: RASGRF3, RAB-INTERACTING FACTOR, RAS-SPECIFIC GUANINE-RELEASING FACTOR 3 
 

Topic mentions per year

Topic mentions per year

1994-2016
0119942016

Papers overview

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2017
2017
Stratum, a Homolog of the Human GEF Mss4, Partnered with Rab8, Controls the Basal Restriction of Basement Membrane Proteins in Epithelial Cells.
The basement membrane (BM), a sheet of extracellular matrix lining the basal side of epithelia, is essential for epithelial cell… (More)
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2017
2017
RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis.
Rab GTPases are switched from their GDP-bound inactive conformation to a GTP-bound active state by guanine nucleotide exchange… (More)
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2009
2009
Rabs and cancer cell motility.
The Rab family of small GTPases functions in regulating vesicular transport in all eukaryotes. In the past few years, several… (More)
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2006
2006
Nucleotide exchange via local protein unfolding--structure of Rab8 in complex with MSS4.
Rab GTPases function as essential regulators of vesicle transport in eukaryotic cells. MSS4 was shown to stimulate nucleotide… (More)
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2006
2006
Purification, crystallization and preliminary X-ray crystallographic analysis of mammalian MSS4-Rab8 GTPase protein complex.
Rab GTPases function as ubiquitous key regulators of membrane-vesicle transport in eukaryotic cells. MSS4 is an evolutionarily… (More)
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2005
2005
Disturbance of sphingolipid biosynthesis abrogates the signaling of Mss4, phosphatidylinositol-4-phosphate 5-kinase, in yeast.
The functional relationships between phosphoinositides and sphingolipids have not been well characterized to date. ISP-1/myriocin… (More)
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1998
1998
Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis.
Phosphatidylinositol 4,5-biphosphate (PtdIns(4,5)P2), an important element in eukaryotic signal transduction, is synthesized… (More)
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1997
1997
Cloning of novel transcripts of the human guanine-nucleotide-exchange factor Mss4: in situ chromosomal mapping and expression in pancreatic cancer.
In a previous large-scale analysis of gene expression in pancreatic cancer using gridded arrays of cDNA libraries and… (More)
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1995
1995
Cloning, Zn2+ binding, and structural characterization of the guanine nucleotide exchange factor human Mss4.
The Sec4/Ypt1/Rab family of small GTP-binding proteins are involved in the regulation of intracellular vesicular transport. A rat… (More)
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1994
1994
Comparison of kinetic properties between MSS4 and Rab3A GRF GDP/GTP exchange proteins.
The kinetic properties of MSS4 are studied in comparison with those of Rab3A GRF. MSS4 stimulates the dissociation of [3H]GDP… (More)
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