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RAB5C gene

Known as: RAB5C, RAB-LIKE, FORMERLY, RAB, member of RAS oncogene family-like 
This gene plays a role in GTP hydrolysis.
National Institutes of Health

Related topics

Related topics

6 relations
EndocytosisGTP BindingHomo sapiensHydrolysis
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Papers overview

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2015
2015
Downregulation of MicroRNA-145 Caused by Hepatitis B Virus X Protein Promotes Expression of CUL5 and Contributes to Pathogenesis of Hepatitis B Virus-Associated Hepatocellular Carcinoma
Background: Hepatitis B viral infection-induced hepatocellular carcinoma (HCC) is a major threat to human health in China… Expand
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Highly Cited
2014
Highly Cited
2014
Cytomegalovirus miRNAs target secretory pathway genes to facilitate formation of the virion assembly compartment and reduce cytokine secretion.
Herpesviruses, including human cytomegalovirus (HCMV), encode multiple microRNAs (miRNA) whose targets are just being uncovered… Expand
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2014
2014
Rab5 Isoforms Orchestrate a “Division of Labor” in the Endocytic Network; Rab5C Modulates Rac-Mediated Cell Motility
Rab5, the prototypical Rab GTPase and master regulator of the endocytic pathway, is encoded as three differentially expressed… Expand
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2014
2014
Identification of PLP2 and RAB5C as novel TPD52 binding partners through yeast two-hybrid screening
Tumor protein D52 (TPD52) is overexpressed in different cancers, but its molecular functions are poorly defined. A large, low… Expand
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Highly Cited
2013
Highly Cited
2013
An Overexpression Screen of Toxoplasma gondii Rab-GTPases Reveals Distinct Transport Routes to the Micronemes
The basic organisation of the endomembrane system is conserved in all eukaryotes and comparative genome analyses provides… Expand
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Highly Cited
2012
Highly Cited
2012
Rab5c promotes AMAP1–PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion
EGF signaling activates Rab5c and promotes the intracellular association of AMAP1 and PRKD2 to enhance β1 integrin recycling and… Expand
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2010
2010
A sequence-based approach to identify reference genes for gene expression analysis
BackgroundAn important consideration when analyzing both microarray and quantitative PCR expression data is the selection of… Expand
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Highly Cited
2009
Highly Cited
2009
Rab5 Isoforms Differentially Regulate the Trafficking and Degradation of Epidermal Growth Factor Receptors*
Ligand-mediated endocytosis is an intricate regulatory mechanism for epidermal growth factor receptor (EGFR) signal transduction… Expand
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1999
1999
The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro.
Rab GTPases play a fundamental role in the regulation of membrane traffic. Three different Rab5 isoforms have been reported but… Expand
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Highly Cited
1995
Highly Cited
1995
Co-operative regulation of endocytosis by three Rab5 isoforms.
Rab proteins are small GTPases involved in the regulation of membrane traffic. Rab5a has been shown to regulate transport in the… Expand
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