Quinuclidinyl Benzilate

Known as: Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 1-azabicyclo(2.2.2)oct-3-yl ester, Benzilate, Quinuclidinyl, Quinuclidinyl Benzilate [Chemical/Ingredient] 
A high-affinity muscarinic antagonist commonly used as a tool in animal and tissue studies.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The parasympathetic branch of the autonomic nervous system regulates the activity of multiple organ systems. Muscarinic receptors… (More)
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Highly Cited
2008
Highly Cited
2008
The objective of this study was to measure the anticholinergic activity (AA) of medications commonly used by older adults. A… (More)
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1993
1993
A loss of acetylcholine is one of the most consistent neurochemical findings in Alzheimer's disease (AD) post-mortem, but the… (More)
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Highly Cited
1993
Highly Cited
1993
Analogues of L-arginine with modifications at the terminal guanidino nitrogen and/or the carboxyl terminus of the molecule have… (More)
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1992
1992
The content of acetylcholine (ACh) in the striatum, brain cortex and hippocampus of rats was lowered 20-180 min after… (More)
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Highly Cited
1984
Highly Cited
1984
Systemic injection of quinuclidinyl benzilate partially abolished low voltage fast activity (LVFA) in the neocortex of waking… (More)
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Highly Cited
1982
Highly Cited
1982
The binding of [3H]nicotine to mouse brain has been measured and subsequently compared with the binding of [125I]alpha… (More)
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1982
1982
A number of analogues of 3-quinuclidinyl benzilate (QNB) have been synthesized and their affinities to muscarinic receptor from… (More)
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1981
1981
A significant decrease in the number of 3H-quinuclidinyl benzilate (3H-QNB) binding sites in striatal membranes was observed in… (More)
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1981
1981
House fly heads contain a binding site for 3-quinuclidinyl benzilate (QNB) that is quite similar in pharmacology to the… (More)
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