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QPCTL gene

Known as: FLJ20084, QPCTL, glutaminyl cyclase-like 
 
National Institutes of Health

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QPCT gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and target for cancer immunotherapy
Cancer cells can evade immune surveillance through the expression of inhibitory ligands that bind their cognate receptors on… Expand
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2019
2019
Two insertion/deletion variants in the promoter region of the QPCTL gene are significantly associated with body weight and carcass traits in chickens.
Glutaminyl-peptide cyclotransferase-like (QPCTL) is an isoenzyme of glutaminyl-peptide cyclotransferase (QPCT). QPCTL and QPCT… Expand
2019
2019
High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
Genome-scale functional genetic screens are used to identify key genetic regulators of a phenotype of interest. However, the… Expand
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2018
2018
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses
Human GWAS of obesity have been successful in identifying loci associated with adiposity, but for the most part, these are non… Expand
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2016
2016
IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes
Abstract Secretory peptides and proteins are frequently modified by pyroglutamic acid (pE, pGlu) at their N-terminus. This… Expand
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2015
2015
A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity
Background:A significant proportion of severe familial forms of obesity remain genetically elusive. Taking advantage of our… Expand
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2013
2013
Role of glutaminyl cyclases in thyroid carcinomas.
CCL2 is a chemokine known to recruit monocytes/macrophages to sites of inflammation. CCL2 is also associated with tumor… Expand
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Highly Cited
2012
Highly Cited
2012
Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations
Objective:Recent genome-wide association studies (GWAS) have identified 38 obesity-associated loci among European populations… Expand
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Highly Cited
2011
Highly Cited
2011
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions
Acute and chronic inflammatory disorders are characterized by detrimental cytokine and chemokine expression. Frequently, the… Expand
2007
2007
글루타미닐 사이클라제에 관련된 신규한 유전자
본 발명은 글루타미닐 사이클라제(QC, EC 2.3.2.5)의 이소효소인 신규한 글루타미닐-펩티드 사이클로트랜스퍼라제-유사 단백질(QPCTL… Expand
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