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Pyrvinium pamoate

 
National Institutes of Health

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2016
2016
Acquisition of chemoresistance and metastatic phenotype are the major causes of breast cancer treatment failure and cancer… Expand
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Highly Cited
2015
Highly Cited
2015
Here, we propose a new strategy for the treatment of early cancerous lesions and advanced metastatic disease, via the selective… Expand
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2012
2012
Pyrvinium pamoate (PP), a classical anthelminthic, potently inhibited proliferation and STAT3 Tyr705 phosphorylation of human… Expand
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Highly Cited
2012
Highly Cited
2012
Pharmacological modification of protein kinase CK1 (casein kinase 1) has previously been shown to influence suicidal erythrocyte… Expand
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Highly Cited
2010
Highly Cited
2010
  • J. Rossignol
  • Experimental parasitology
  • 2010
  • Corpus ID: 32931638
Cryptosporidium species and Giardia intestinalis are the most common enteric protozoan pathogens affecting humans worldwide. In… Expand
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2008
2008
ABSTRACT No effective approved drug therapy exists for Cryptosporidium infection of immunocompromised patients. Here we… Expand
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2008
2008
We identified pyrvinium pamoate, an old anthelminthic medicine, which preferentially inhibits anchorage-independent growth of… Expand
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Highly Cited
2004
Highly Cited
2004
An anthelminthic, pyrvinium pamoate (PP), 6‐(dimethylamino)‐2‐[2‐(2,5‐dimethyl‐1‐phenyl‐1H‐pyrrol‐3‐yl)ethenyl]‐1‐methyl‐quino… Expand
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1976
1976
Pyrvinium pamoate, tablets and suspension, was administered as single 350‐mg doses to 12 healthy male volunteers to determine… Expand
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1959
1959
Summary A pinworm study employing pyrvinium chloride and pyrvinium pamoate is described. Differences in toxicity indicate the… Expand
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