Pyrvinium pamoate

 
National Institutes of Health

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2016
2016
Acquisition of chemoresistance and metastatic phenotype are the major causes of breast cancer treatment failure and cancer… (More)
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2014
2014
The in vitro and in vivo effects of pyrvinium pamoate (PP), a newly identified WNT signaling inhibitor, were evaluated against… (More)
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2013
2013
The serotonin receptor 2C plays a central role in mood and appetite control. It undergoes pre-mRNA editing as well as alternative… (More)
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2013
2013
WNT signaling plays a key role in the self-renewal of tumor initiation cells (TICs). In this study, we used pyrvinium pamoate (PP… (More)
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2012
2012
Pharmacological modification of protein kinase CK1 (casein kinase 1) has previously been shown to influence suicidal erythrocyte… (More)
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2012
2012
Pyrvinium pamoate (PP), a classical anthelminthic, potently inhibited proliferation and STAT3 Tyr705 phosphorylation of human… (More)
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2012
2012
Increased glycolysis is the principal explanation for how cancer cells generate energy in the absence of oxygen. However, in… (More)
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2008
2008
No effective approved drug therapy exists for Cryptosporidium infection of immunocompromised patients. Here we investigated the… (More)
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1976
1976
Pyrvinium pamoate, tablets and suspension, was administered as single 350-mg doses to 12 healthy male volunteers to determine… (More)
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1974
1974
Pyrvinium pamoate (0-500 nM) inhibits proliferation of MCF-7 (luminal), MDA-MB-231 (claudin-low), MDA-MB-468 (basal-like) and… (More)
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