Pyruvate Metabolism Pathway

Known as: Pyruvate Metabolism, pyruvate metabolic process 
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. [GOC:go_curators]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Mutant isocitrate dehydrogenase 1 (IDH1) catalyzes the production of 2-hydroxyglutarate but also elicits additional metabolic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2013
Review
2013
Pyruvate is a keystone molecule critical for numerous aspects of eukaryotic and human metabolism. Pyruvate is the end-product of… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. Many tumor cells… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Renal cell carcinoma (RCC) is the sixth leading cause of cancer death and is responsible for 11,000 deaths per year in the US… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Cell lines are used in experimental investigation of cancer but their capacity to represent tumor cells has yet to be quantified… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The brain keenly depends on glucose for energy, and mammalians have redundant systems to control glucose production. An increase… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Aerobic and anaerobic central metabolism of Saccharomyces cerevisiae cells was explored in batch cultures on a minimal medium… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Islet beta-cells express low levels of lactate dehydrogenase and have high glycerol phosphate dehydrogenase activity. To… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1986
1986
Hydrogenosomes isolated from Tritrichomonas foetus and Trichomonas vaginalis fermented pyruvate to acetate, malate, H2, and CO2… (More)
Is this relevant?