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Pyruvate Dehydrogenase (Lipoamide)-Phosphatase

Known as: Phosphatase, Pyruvate Dehydrogenase, PDH Phosphatase, Phosphatase, PDH 
(Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a… 
National Institutes of Health

Related topics

Related topics

10 relations
In BloodPDP1 geneProcess of secretionantagonists & inhibitors

Broader (1)

Phosphoric Monoester Hydrolases

Narrower (1)

Pyruvate dehydrogenase phosphatase deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Atomic resolution neutron holography ( present status and future prospects )
The idea of atomic resolution neutron holography proposed by the authors of the present talk has been experimentally proven using… 
2005
2005
Role of Calcium Ions in the Regulation of Intramitochondrial Metabolism
1. Increasing concentrations of both Ca2+ and Sr2+ (generated by using EGTA buffers) resulted in 4-fold increases in the initial… 
1984
1984
Persistence of the effect of insulin on pyruvate dehydrogenase activity in rat white and brown adipose tissue during the preparation and subsequent incubation of mitochondria.
Increases in the amount of the active non-phosphorylated form of pyruvate dehydrogenase in rat epididymal adipose tissue, as a… 
Highly Cited
1981
Highly Cited
1981
Effect of micromolar concentrations of free Ca2+ ions on pyruvate dehydrogenase interconversion in intact rat heart mitochondria.
1. The mitochondrial content of active (dephospho) pyruvate dehydrogenase (PDHA) was found to be severalfold higher at an… 
1981
1981
The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation.
1. Incubation of mitochondria from heart, liver and kidney with [32P]phosphate allowed 32P incorporation into two… 
1980
1980
Effect of phenformin on the metabolism of glucose, pyruvate and acetate in guinea-pig heart.
In the isolated perfused heart of the guinea-pig, phenformin could be shown to have a characteristic effect on cardiac… 
1978
1978
Conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active complex by the phosphate reaction in heart mitochondria is inhibited by alloxan-diabetes or starvation in the rat.
1. The conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active (dephosphorylated) complex by pyruvate… 
1978
1978
Lactic acidosis due to a defect in the pyruvate dehydrogenase complex: a possible brain pyruvate dehydrogenase phosphatase deficiency.
Highly Cited
1976
Highly Cited
1976
Glucose metabolism in perfused skeletal muscle. Pyruvate dehydrogenase activity in starvation, diabetes and exercise.
1. The interconversion of pyruvate dehydrogenase between its inactive phosphorylated and active dephosphorylated forms was… 
1975
1975
The role of mitochondria in the contraction-relaxation cycle and other Ca2+-dependent activities of heart cells.
The problem of whether mitochondria participate in the contraction and relaxation of heart by binding Ca2+ reversibly has been… 
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