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Pulmonary Surfactant-Associated Protein A

Known as: SP-A Protein, Surfactant Protein A, Pulmonary Surfactant Associated Protein A 
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The pulmonary innate immune system responds to various airborne microbes. Although its specificity is broad and based on the… Expand
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Highly Cited
2001
Highly Cited
2001
Surfactant protein A (SP-A) is an innate immune molecule that binds foreign organisms that invade the lungs and targets them for… Expand
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Highly Cited
1997
Highly Cited
1997
The complement protein C1q, mannose-binding lectin (MBL), and pulmonary surfactant protein A (SPA) are structurally similar… Expand
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Highly Cited
1996
Highly Cited
1996
Surfactant protein A (SP-A) regulates alveolar macrophage function and has been implicated in the mediation of pulmonary host… Expand
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Highly Cited
1995
Highly Cited
1995
During initial infection with Mycobacterium tuberculosis, bacteria that reach the distal airspaces of the lung are phagocytosed… Expand
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Highly Cited
1995
Highly Cited
1995
Cis-acting elements determining lung epithelial cell-selective transcription of the murine surfactant protein A (SP-A) gene were… Expand
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Highly Cited
1993
Highly Cited
1993
An enzyme-linked immunosorbent assay using monoclonal antibodies to human lung surfactant protein A (SP-A) was applied to sera… Expand
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Highly Cited
1993
Highly Cited
1993
Pulmonary surfactant modulates several functions of alveolar macrophages including phagocytosis, killing, and chemotaxis. We… Expand
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Highly Cited
1990
Highly Cited
1990
The effects of surfactant, surfactant lipids, and surfactant protein A (SP-A) on the surface phagocytosis of [3H]thymidine… Expand
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Highly Cited
1988
Highly Cited
1988
Primary cultures of rat alveolar type II cells bind radiolabeled pulmonary surfactant protein A (SP-A) with high affinity. The… Expand
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