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Pteridinones

Pteridines with a 4-keto OXYGEN.
National Institutes of Health

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Pteridines

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2018
2018
Transition-Metal-Free С–С Coupling of 5,7-Dihydroxybenzopyrones with Quinoxalones and Pteridinones
A new synthetic protocol for nucleophilic substitution of hydrogen­ in quinoxalones and pteridinones by the action of 5,7-di… Expand
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2010
2010
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
Pteridinones were designed based on a non-selective kinase template. Because of the uniqueness of the PI3K and mTOR binding… Expand
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2005
2005
Pteridinones utilisees en tant qu'inhibiteurs des plk (polo-like-kinases)
L'invention concerne des composes de formule generale (I), dans laquelle L, Q1, Q2, X, Y, Ra, Rb, Rc, R1, R2, R3 et R4 sont tels… Expand
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1993
1993
The synthesis of fluorine-containing pterins.
The introduction of fluorine into molecules has been well demonstrated to modify the biological properties significantly1. In… Expand
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