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Pteridinones
Pteridines with a 4-keto OXYGEN.
National Institutes of Health
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Pteridines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Molecular docking of substituted pteridinones and pyrimidines to the ATP-binding site of the N-terminal domain of RSK2 and associated MM/GBSA and molecular field datasets
Kimberly A Casalvieri
,
Christopher J. Matheson
,
D. Backos
,
Philip Reigan
Data in brief
2020
Corpus ID: 214074248
The data have been obtained for a series of substituted pteridinones and pyrimidines that were developed based on BI-D1870 to…
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2020
2020
Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study.
Kimberly A Casalvieri
,
Christopher J. Matheson
,
D. Backos
,
P. Reigan
Bioorganic & medicinal chemistry
2020
Corpus ID: 210924373
The activity of p90 ribosomal S6 kinase 2 (RSK2) has emerged as an attractive target for cancer therapy due to its role in the…
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2018
2018
Transition-Metal-Free С–С Coupling of 5,7-Dihydroxybenzopyrones with Quinoxalones and Pteridinones
I. A. Khalymbadzha
,
R. Fatykhov
,
+7 authors
V. Kartsev
2018
Corpus ID: 102992334
A new synthetic protocol for nucleophilic substitution of hydrogen in quinoxalones and pteridinones by the action of 5,7-di…
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2010
2010
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
K. Liu
,
S. Bagrodia
,
+21 authors
Aihua Zou
Bioorganic & medicinal chemistry letters
2010
Corpus ID: 206246319
Pteridinones were designed based on a non-selective kinase template. Because of the uniqueness of the PI3K and mTOR binding…
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2005
2005
Pteridinones utilisees en tant qu'inhibiteurs des plk (polo-like-kinases)
H. Stadtmueller
,
H. Engelhardt
,
A. Schoop
,
M. Steegmaier
2005
Corpus ID: 103632702
L'invention concerne des composes de formule generale (I), dans laquelle L, Q1, Q2, X, Y, Ra, Rb, Rc, R1, R2, R3 et R4 sont tels…
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1993
1993
The synthesis of fluorine-containing pterins.
C. Dunn
,
C. Gibson
,
C. Suckling
,
W. Xing
Advances in experimental medicine and biology
1993
Corpus ID: 26778121
The introduction of fluorine into molecules has been well demonstrated to modify the biological properties significantly1. In…
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