Proximal Interphalangeal Joint 4
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The heterodimeric eukaryotic Drs2p-Cdc50p complex is a lipid flippase that maintains cell membrane asymmetry. The enzyme complex… Expand Summary Phosphatidylinositol 3,4,5-trisphosphate (PIP3) generation at the plasma membrane is a key event during activation of… Expand Phosphatidylinositol 5 phosphate 4-kinase (PIP4K) are enzymes that catalyse the phosphorylation of phosphatidylinositol 5… Expand The discovery of the causative gene for Huntington’s disease (HD) has promoted numerous efforts to uncover cellular pathways that… Expand Achieving robust cancer-specific lethality is the ultimate clinical goal. Here, we identify a compound with dual-inhibitory… Expand ABSTRACT Endocytic turnover is essential for the regulation of the protein composition and function of the plasma membrane, and… Expand During development, Drosophila larvae undergo a dramatic increase in body mass wherein nutritional and developmental cues are… Expand Increasing the abundance of the phospholipid PtdIns5P protects cells from oxidative stress. Stress-Resisting Phosphoinositide… Expand The beta-isoform of PIP4K (PtdIns5P-4-kinase) regulates the levels of nuclear PtdIns5P, which in turn modulates the acetylation… Expand Phosphatidylinositol-5-phosphate (PI-5-P) is a newly identified phosphoinositide with characteristics of a signaling lipid but no… Expand