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Proximal Interphalangeal Joint 4
Known as:
PIP4
A ginglymoid (hinge) synovial joint within the fourth digit of the hand or foot connecting the proximal and middle phalanges.
National Institutes of Health
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Related topics
Related topics
4 relations
Body part
CDISC SDTM Anatomical Location Terminology
Clinical Data Interchange Standards Consortium Terminology
Skeletal system
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Autoinhibition and activation mechanisms of the eukaryotic lipid flippase Drs2p-Cdc50p
Lin Bai
,
A. Kovach
,
Q. You
,
H. Hsu
,
Gongpu Zhao
,
Huilin Li
Nature Communications
2019
Corpus ID: 202557908
The heterodimeric eukaryotic Drs2p-Cdc50p complex is a lipid flippase that maintains cell membrane asymmetry. The enzyme complex…
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2019
2019
Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane PIP3 Turnover and Insulin Signaling
Sanjeev Sharma
,
Swarna Mathre
,
Visvanathan Ramya
,
Dhananjay Shinde
,
P. Raghu
Cell reports
2019
Corpus ID: 155100891
2019
2019
Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes
Swarna Mathre
,
K. B. Reddy
,
Visvanathan Ramya
,
Harini Krishnan
,
Avishek Ghosh
,
P. Raghu
Bioscience reports
2019
Corpus ID: 73433896
Phosphatidylinositol 5 phosphate 4-kinase (PIP4K) are enzymes that catalyse the phosphorylation of phosphatidylinositol 5…
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2017
2017
Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality
Mayumi Kitagawa
,
Pei-Ju Liao
,
+16 authors
Sang Hyun Lee
Nature Communications
2017
Corpus ID: 23305268
Achieving robust cancer-specific lethality is the ultimate clinical goal. Here, we identify a compound with dual-inhibitory…
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2017
2017
Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
I. Al-Ramahi
,
S. Giridharan
,
+17 authors
J. Marugan
eLife
2017
Corpus ID: 2132840
The discovery of the causative gene for Huntington’s disease (HD) has promoted numerous efforts to uncover cellular pathways that…
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Review
2015
Review
2015
PIP4K and the role of nuclear phosphoinositides in tumour suppression.
R. Fiume
,
Yvette Stijf-Bultsma
,
+4 authors
N. Divecha
Biochimica et biophysica acta
2015
Corpus ID: 26669213
Highly Cited
2013
Highly Cited
2013
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development
Amit Gupta
,
Sarah Toscano
,
+5 authors
P. Raghu
Proceedings of the National Academy of Sciences
2013
Corpus ID: 23018188
During development, Drosophila larvae undergo a dramatic increase in body mass wherein nutritional and developmental cues are…
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2012
2012
Regulation of Phosphatidylinositol-5-Phosphate Signaling by Pin1 Determines Sensitivity to Oxidative Stress
Willem-Jan Keune
,
David R. Jones
,
+4 authors
N. Divecha
Science Signaling
2012
Corpus ID: 9074840
Increasing the abundance of the phospholipid PtdIns5P protects cells from oxidative stress. Stress-Resisting Phosphoinositide…
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Highly Cited
2010
Highly Cited
2010
PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha.
Yvette Bultsma
,
Willem-Jan Keune
,
N. Divecha
The Biochemical journal
2010
Corpus ID: 206149775
The beta-isoform of PIP4K (PtdIns5P-4-kinase) regulates the levels of nuclear PtdIns5P, which in turn modulates the acetylation…
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Highly Cited
2003
Highly Cited
2003
The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation
V. Carricaburu
,
K. Lamia
,
+4 authors
L. Rameh
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 24521062
Phosphatidylinositol-5-phosphate (PI-5-P) is a newly identified phosphoinositide with characteristics of a signaling lipid but no…
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