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Protocollagen

A precursor of procollagen consisting of procollagen peptide chains in which proline and lysine have not yet been hydroxylated.
National Institutes of Health

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Procollagen

Papers overview

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Highly Cited
1974
Highly Cited
1974
Collagen biosynthesis. Characterization of subcellular fractions from embyonic chick fibroblasts and the intracellular localization of protocollagen prolyl and protocollagen lysyl hydroxylases.
1. Subcellular fractions of freshly isolated matrix-free embryonic chick tendon and sternal cartilage cells have been… 
Highly Cited
1974
Highly Cited
1974
Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.
Cells liberated from the tendons of chick embryos by controlled enzymic digestion were used to examine the synthesis of the… 
1973
1973
Structure of protocollagen proline hydroxylase from chick embryos.
Protocollagen proline hydroxylase was purified from chick embryos with an affinity-column procedure which yielded pure enzyme in… 
Highly Cited
1972
Highly Cited
1972
Studies on protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of -ketoglutarate.
1971
1971
Synthesis and enzymic hydroxylation of protocollagen model peptide containing a hydroxyproline residue.
1. Two protocollagen model peptides, Z-Gly-Pro-Hyp-Gly-(Pro-Pro-Gly)(5) (Z, benzyloxycarbonyl) and AOC-(Pro-Pro-Gly)(6) (AOC… 
1970
1970
Protocollagen proline hydroxylase of the mouse uterus during pregnancy and post-partum involution.
1. The protocollagen proline hydroxylase in mouse uterus was found to be similar to that in other animal sources in its… 
1969
1969
Protocollagen proline hydroxylase from Ascaris lumbricoides.
Abstract An enzyme was found in the muscle layers of Ascaris lumbricoides which was similar to the protocollagen proline… 
1969
1969
The enzymic hydroxylation of protocollagen models.
1. Synthetic polymers of l-prolyl-l-prolylglycine of defined chain length, (Pro-Pro-Gly)(n), were found to be substrates for the… 
1969
1969
Effect of endometrial phase, ovariectomy, estradiol and progesterone on uterine protocollagen hydroxylase.
Protocollagen hydroxylase activity was assayed in porcine uteri in relation to endometrial phases and pregnancy. The highest… 
Review
1968
Review
1968
The synthesis of collagen and protocollagen hydroxylase by fibroblastic and nonfibroblastic cell lines.
We have earlier surveyed a variety of fibroblastic and nonfibroblastic cell types for their capacity to synthesize collagen in… 
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