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Proto-Oncogene Proteins c-bcl-2

Known as: c-bcl-2 Proteins, bcl-2 Proto-Oncogene Proteins, bcl 2 Proto Oncogene Proteins 
Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2007
Highly Cited
2007
Bcl-2 is an anti-apoptotic oncoprotein and its protein levels are inversely correlated with prognosis in many cancers. However… 
Highly Cited
2002
Highly Cited
2002
Multiple myeloma (MM) is a plasma cell malignancy that occurs mainly in bone marrow. As MM cells proliferate slowly, it would… 
Highly Cited
2001
Highly Cited
2001
The Bcl-2 family of proteins plays a central regulatory role in apoptosis. We have identified a novel, widely expressed Bcl-2… 
Highly Cited
1998
Highly Cited
1998
Malignant melanoma is a prime example of cancers that respond poorly to various treatment modalities including chemotherapy1. A… 
Highly Cited
1998
Highly Cited
1998
An immunohistochemical study to determine the pattern of immunoreactivity for bcl-2 oncoprotein was performed in 380 spindle cell… 
Highly Cited
1996
Highly Cited
1996
The Bcl-2 oncoprotein, which is expressed in a variety of human malignancies, blocks apoptosis induced by chemotherapeutic drugs… 
Highly Cited
1995
Highly Cited
1995
Previous studies have implicated the bcl-2 protooncogene as a potential regulator of neuronal survival. However, mice lacking… 
Highly Cited
1993
Highly Cited
1993
A multidisciplinary approach was taken to investigate the intracellular locations of the 26-kDa integral membrane protein encoded…