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Protein-tyrosine kinase inhibitor

Known as: Tyrosine Kinase Inhibitor, TK Inhibitors, Protein Tyrosine Kinase Inhibitors 
Any substance that inhibits tyrosine kinase, an enzyme involved in the transduction and processing of many extracellular and intracellular signals… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK) and is effective in chronic lymphocytic… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis of gastrointestinal stromal… 
Highly Cited
2000
Highly Cited
2000
STI571 (formerly known as CGP 57148B) is a protein-tyrosine kinase inhibitor that is currently in clinical trials for the… 
Highly Cited
2000
Highly Cited
2000
STI 571 (formerly known as CGP 57148B) is a known inhibitor of the c-abl, bcr-abl, and platelet-derived growth-factor receptor… 
Review
2000
Review
2000
Protein kinases are a large family of homologous proteins comprising 2 major subfamilies, the protein serine/threonine kinases… 
Highly Cited
1997
Highly Cited
1997
A new class of protein tyrosine kinase inhibitors was identified that is based on an oxindole core (indolinones). Two compounds… 
Highly Cited
1996
Highly Cited
1996
Here, we have studied the activity of a novel protein-tyrosine kinase inhibitor that is selective for the Src family of tyrosine…