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Protein p53

Known as: Tumor Protein p53, p53 proteins, Tumor Suppressor Protein p53 [Chemical/Ingredient] 
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent… 
National Institutes of Health

Papers overview

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Review
2008
Review
2008
The p53 protein regulates the transcription of many different genes in response to a wide variety of stress signals. Following… 
Highly Cited
2004
Highly Cited
2004
MDM2 binds the p53 tumor suppressor protein with high affinity and negatively modulates its transcriptional activity and… 
Review
2002
Review
2002
Compared with many normal tissues, cancer cells are highly sensitized to apoptotic signals, and survive only because they have… 
Review
1997
Highly Cited
1997
Highly Cited
1997
The tumour-suppressor p53 is a short-lived protein that is maintained at low, often undetectable, levels in normal cells… 
Highly Cited
1993
Highly Cited
1993
The p53 protein can bind to a set of specific DNA sequences, and this may activate the transcription of genes adjacent to these… 
Highly Cited
1991
Highly Cited
1991
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could… 
Highly Cited
1990
Highly Cited
1990
Human papillomavirus type 16 (HPV-16) is a DNA tumor virus that is associated with human anogenital cancers and encodes two…