Protein family

Known as: Enzyme family, Protein families, Family (disambiguation) 
A protein family is a group of evolutionarily-related proteins. In many cases a protein family has a corresponding gene family, in which each gene… (More)
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Highly Cited
2016
Highly Cited
2016
In the last two years the Pfam database (http://pfam.xfam.org) has undergone a substantial reorganisation to reduce the effort… (More)
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Highly Cited
2016
Highly Cited
2016
PANTHER (Protein Analysis THrough Evolutionary Relationships, http://pantherdb.org) is a widely used online resource for… (More)
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Highly Cited
2012
Highly Cited
2012
Pfam is a widely used database of protein families, currently containing more than 13,000 manually curated protein families as of… (More)
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Highly Cited
2011
Highly Cited
2011
The similarity in the three-dimensional structures of homologous proteins imposes strong constraints on their sequence… (More)
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Highly Cited
2005
Highly Cited
2005
PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human… (More)
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Highly Cited
2005
Highly Cited
2005
Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic… (More)
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Highly Cited
2004
Highly Cited
2004
MOTIVATION Classification of proteins sequences into functional and structural families based on sequence homology is a central… (More)
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Highly Cited
2003
Highly Cited
2003
TIGRFAMs is a collection of manually curated protein families consisting of hidden Markov models (HMMs), multiple sequence… (More)
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Highly Cited
1998
Highly Cited
1998
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The… (More)
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Highly Cited
1994
Highly Cited
1994
Signature databases are vital tools for identifying distant relationships in novel sequences and hence for inferring protein… (More)
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