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Protein Sprouty Homolog 4

Known as: SPRY4, Spry-4 
Protein sprouty homolog 4 (299 aa, ~33 kDa) is encoded by the human SPRY4 gene. This protein plays a role in the inhibition of receptor-mediated… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Abstract Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in human cancer biology. In… Expand
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Highly Cited
2016
Highly Cited
2016
UNLABELLED KRAS is frequently mutated in lung cancer. Whereas MAPK is a well-known effector pathway of KRAS, blocking this… Expand
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Highly Cited
2015
Highly Cited
2015
BackgroundLong noncoding RNAs (lncRNAs) are emerging as key regulators governing fundamental biological processes, and their… Expand
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Highly Cited
2015
Highly Cited
2015
BackgroundLong noncoding RNAs (lncRNAs) have emerged recently as a new class of genes that regulate cellular processes, such as… Expand
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Highly Cited
2014
Highly Cited
2014
Recent evidence indicates that long noncoding RNAs (lncRNAs) have a critical role in the regulation of cellular processes such as… Expand
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Highly Cited
2013
Highly Cited
2013
Congenital hypogonadotropic hypogonadism (CHH) and its anosmia-associated form (Kallmann syndrome [KS]) are genetically… Expand
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Highly Cited
2008
Highly Cited
2008
Rodent incisors grow throughout adult life, but are prevented from becoming excessively long by constant abrasion, which is… Expand
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Highly Cited
2006
Highly Cited
2006
Because the Sprouty (Spry) proteins were shown to be inhibitors of the mainstream Ras/ERK pathway, there has been considerable… Expand
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Highly Cited
2004
Highly Cited
2004
BRAF mutations result in constitutively active BRAF kinase activity and increased extracellular signal-regulated kinase (ERK… Expand
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Highly Cited
2001
Highly Cited
2001
In looking for novel factors involved in the regulation of the fibroblast growth factor (FGF) signaling pathway, we have isolated… Expand
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