Protein Sprouty Homolog 4
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Abstract Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in human cancer biology. In… Expand UNLABELLED
KRAS is frequently mutated in lung cancer. Whereas MAPK is a well-known effector pathway of KRAS, blocking this… Expand BackgroundLong noncoding RNAs (lncRNAs) are emerging as key regulators governing fundamental biological processes, and their… Expand BackgroundLong noncoding RNAs (lncRNAs) have emerged recently as a new class of genes that regulate cellular processes, such as… Expand Recent evidence indicates that long noncoding RNAs (lncRNAs) have a critical role in the regulation of cellular processes such as… Expand Congenital hypogonadotropic hypogonadism (CHH) and its anosmia-associated form (Kallmann syndrome [KS]) are genetically… Expand Rodent incisors grow throughout adult life, but are prevented from becoming excessively long by constant abrasion, which is… Expand Because the Sprouty (Spry) proteins were shown to be inhibitors of the mainstream Ras/ERK pathway, there has been considerable… Expand BRAF mutations result in constitutively active BRAF kinase activity and increased extracellular signal-regulated kinase (ERK… Expand In looking for novel factors involved in the regulation of the fibroblast growth factor (FGF) signaling pathway, we have isolated… Expand