Protein Phosphatase 2A

Known as: Protein Phosphatase-2A, PP2A, Protein Phosphatase 2 [Chemical/Ingredient] 
PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
010020019842017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Entry into mitosis in eukaryotes requires the activity of cyclin-dependent kinase 1 (Cdk1). Cdk1 is opposed by protein… (More)
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Highly Cited
2010
Highly Cited
2010
Hyperphosphorylated tau plays an important role in the formation of neurofibrillary tangles in brains of patients with Alzheimer… (More)
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Highly Cited
2007
Highly Cited
2007
Protein phosphatase 2A (PP2A) is a principal Ser/Thr phosphatase, the deregulation of which is associated with multiple human… (More)
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Highly Cited
2006
Highly Cited
2006
Sister chromatid cohesion, mediated by a complex called cohesin, is crucial—particularly at centromeres—for proper chromosome… (More)
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Highly Cited
2006
Highly Cited
2006
Protein Phosphatase 2A (PP2A) plays an essential role in many aspects of cellular physiology. The PP2A holoenzyme consists of a… (More)
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Highly Cited
2006
Highly Cited
2006
The serine/threonine phosphatase protein phosphatase 2A (PP2A) plays an essential role in many aspects of cellular functions and… (More)
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Highly Cited
2002
Highly Cited
2002
Tight junctions (TJs) play a crucial role in the establishment of cell polarity and regulation of paracellular permeability in… (More)
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Highly Cited
2000
Highly Cited
2000
On TGF-beta binding, the TGF-beta receptor directly phosphorylates and activates the transcription factors Smad2/3, leading to G… (More)
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Highly Cited
1994
Highly Cited
1994
LONG-TERM potentiation (LTP) is a synaptic mechanism thought to be involved in learning and memory1. Long-term depression (LTD… (More)
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Highly Cited
1990
Highly Cited
1990
The cyclic heptapeptide, microcystin-LR, inhibits protein phosphatases 1 (PP1) and 2A (PP2A) with Ki values below 0.1 nM. Protein… (More)
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