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Protein Kinase C Inhibitor

Any substance that inhibits protein kinase c (PKC), a serine/threonine protein kinase that catalyzes certain cell protein phosphorylation reactions… 
National Institutes of Health

Papers overview

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2020
2020
Circulating tumor DNA (ctDNA) in patients (pts) with metastatic uveal melanoma (UM) treated with protein kinase C inhibitor (PKCi).
e22054Background: UM is the most common primary intraocular malignancy. About 50% of pts with UM will develop metastatic disease… 
2014
2014
Engineering a delta protein kinase C inhibitor that selectively inhibits interaction and phosphorylation of one substrate of the multi‐substrate kinase (582.3)
Rationale: Many kinases phosphorylate multiple substrates. To assess the role of an individual phosphorylation event without… 
2012
2012
[Screening and identification of receptor reacting with nucleocapsid protein of duck enteritis virus].
To clarify the pathogenesis of Duck enteritis virus (DEV), the cDNA library of duck's liver infected by DEV and a bait plasmid… 
2001
2001
Effect of protein kinase C inhibitor (PKCI) on radiation sensitivity and c-fos transcription.
1998
1998
Cardiorespiratory responses to systemic administration of a protein kinase C inhibitor in conscious rats.
Although protein kinase C (PKC) is an essential component of multiple neurally mediated events, its role in respiratory control… 
1998
1998
Dysmorphogenic effects of a specific protein kinase C inhibitor during neurulation.
1997
1997
Dissociation of tyrosine phosphorylation and activation of phosphoinositide phospholipase C induced by the protein kinase C inhibitor Ro-31-8220 in Swiss 3T3 cells treated with platelet-derived…
1996
1996
G-protein βγ Subunits Mediate Specific Phosphorylation of the Protein-tyrosine Phosphatase SH-PTP1 Induced by Lysophosphatidic Acid*
SH-PTP1 is a protein-tyrosine phosphatase preferentially expressed in hematopoietic cells and bearing two SH2 (rc homology-2… 
1995
1995
Activation of the plasma membrane chloride channel by protein kinase C in isolated guinea‐pig hepatocytes.
1. To assess the nature of the underlying mechanism of noradrenaline‐induced increase of Cl‐ conductances in hepatocytes… 
1995
1995
Independent signal transduction pathways for IL-1 and TNF in LPS-tolerant macrophages.
Macrophages rendered "tolerant" by pretreatment with low-dose endotoxin (LPSp) release less TNF and more IL-1 in response to a… 
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