Prostaglandin Endoperoxides

Known as: Endoperoxides, Prostaglandin, Prostaglandin Endoperoxides [Chemical/Ingredient], prostaglandin endoperoxide 
Precursors in the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. They are physiologically active compounds, having effect on… (More)
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
Previously, we have shown that forced expression of prostaglandin endoperoxide synthase-2 [also called cyclooxygenase (COX) 2… (More)
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Highly Cited
1994
Highly Cited
1994
The aim of our study was to characterize a model of human prostaglandin endoperoxide synthase-2 (PGHS-2) expression allowing the… (More)
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Highly Cited
1993
Highly Cited
1993
Murine prostaglandin endoperoxide (PGH) synthase-1 and PGH synthase-2 expressed in cos-1 cells were found to be differentially… (More)
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Highly Cited
1976
Highly Cited
1976
Microsomes prepared from rabbit or pig aortas transformed endoperoxides (PGG2 or PGH2) to an unstable substance (PGX) that… (More)
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Highly Cited
1976
Highly Cited
1976
Fresh arterial tissue generates an unstable substance (prostablandin X) which relaxes vascular smooth muscle and potently… (More)
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Highly Cited
1976
Highly Cited
1976
Prostaglandin (PG) endoperoxides (PGG2 and PGH2) contract arterial smooth muscle and cause platelet aggregation. Microsomes from… (More)
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Highly Cited
1976
Highly Cited
1976
The microsomal fraction of horse and human platelets contains an enzyme which converts prostaglandin cyclic endoperoxides (PGG2… (More)
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Highly Cited
1975
Highly Cited
1975
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of… (More)
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Highly Cited
1974
Highly Cited
1974
Arachidonic acid incubated with human platelets was converted into three compounds, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid… (More)
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Highly Cited
1974
Highly Cited
1974
Incubation for a short time of arachidonic acid with the microsomal fraction of a homogenate of the vesicular gland of sheep in… (More)
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