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Prostaglandin E2 Receptor EP4 Subtype

Known as: PGE2 Receptor EP4 Subtype, Prostanoid EP4 Receptor, PGE Receptor EP4 Subtype 
Prostaglandin E2 receptor EP4 subtype (488 aa, ~53 kDa) is encoded by the human PTGER4 gene. This protein plays a role in the regulation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
PGE2 is a potent lipid mediator involved in maintaining homeostasis but also promotion of acute inflammation or immune… Expand
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Highly Cited
2010
Highly Cited
2010
Peripheral inflammation leads to immune responses in brain characterized by microglial activation, elaboration of proinflammatory… Expand
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Highly Cited
2009
Highly Cited
2009
Prostaglandins, particularly prostaglandin E2 (PGE2), play an important role during inflammation. This is exemplified by the… Expand
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Highly Cited
2008
Highly Cited
2008
PGE2 has been shown to induce relaxations in precontracted human pulmonary venous preparations, while in pulmonary arteries this… Expand
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Highly Cited
2006
Highly Cited
2006
The control of dendritic cell (DC) migration is pivotal for the initiation of cellular immune responses. In this study, we… Expand
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Highly Cited
2003
Highly Cited
2003
We have reported previously that PGE2 inhibits dendritic cells (DC) functions. Because E prostanoid receptor (EPR) subtypes… Expand
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Highly Cited
2003
Highly Cited
2003
Prostaglandin E2(PGE2) has a strong protective effect on the gastric mucosain vivo; however, the molecular mechanism of a direct… Expand
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Highly Cited
2002
Highly Cited
2002
Bone remodeling, comprising resorption of existing bone and de novo bone formation, is required for the maintenance of a constant… Expand
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Highly Cited
2002
Highly Cited
2002
Pro-inflammatory pathways participate in the pathogenesis of atherosclerosis. However, the role of endogenous anti-inflammatory… Expand
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Highly Cited
1997
Highly Cited
1997
We have characterized the rat prostanoid EP1, EP2, EP3alpha and EP4 receptor subtypes cloned from spleen, hepatocyte and/or… Expand
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