Prostaglandin E2 Receptor EP4 Subtype

Known as: PGE2 Receptor EP4 Subtype, Prostanoid EP4 Receptor, PGE Receptor EP4 Subtype 
Prostaglandin E2 receptor EP4 subtype (488 aa, ~53 kDa) is encoded by the human PTGER4 gene. This protein plays a role in the regulation of… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Prostaglandins, particularly prostaglandin E2 (PGE2), play an important role during inflammation. This is exemplified by the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
BACKGROUND AND PURPOSE PGE2 has been shown to induce relaxations in precontracted human pulmonary venous preparations, while in… (More)
Is this relevant?
2007
2007
The predominant product of cyclooxygenase (COX) activity in the colon, prostaglandin (PG) E2 promotes intestinal tumorigenesis… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Cyclooxygenase-2 and prostaglandin E(2) (PGE(2)) levels are increased in colorectal cancers and a subset of adenomas. PGE(2… (More)
Is this relevant?
2005
2005
PGE(2) and PGI(2) stimulate renin secretion and cAMP accumulation in juxtaglomerular granular (JG) cells. We addressed, at the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2003
Highly Cited
2003
We have reported previously that PGE(2) inhibits dendritic cells (DC) functions. Because E prostanoid receptor (EPR) subtypes… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Prostaglandin E(2) (PGE(2)) has a strong protective effect on the gastric mucosa in vivo; however, the molecular mechanism of a… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Pro-inflammatory pathways participate in the pathogenesis of atherosclerosis. However, the role of endogenous anti-inflammatory… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Bone remodeling, comprising resorption of existing bone and de novo bone formation, is required for the maintenance of a constant… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
1997
1997
The 488-amino acid human prostaglandin E2 receptor EP4 subtype, which couples to stimulation of adenylyl cyclase, shares the… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?