Proprotein Convertase Subtilisin/Kexin Type 9 Measurement

Known as: PCSK9, Proprotein Convertase Subtilisin/Kexin 9 
The determination of the proprotein convertase subtilisin/kexin type 9 present in a sample.

Topic mentions per year

Topic mentions per year

2004-2018
010020030020042018

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to LDL receptors, leading to their degradation. Genetics… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVES The primary objective of this study was to evaluate the low-density lipoprotein cholesterol (LDL-C)-lowering efficacy… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND LDL cholesterol (LDL-C) is a well established risk factor for cardiovascular disease. Proprotein convertase subtilisin… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Despite statin treatment, many patients with heterozygous familial hypercholesterolemia do not reach desired low… (More)
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2012
2012
BACKGROUND The proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes independently of its enzymatic activity the… (More)
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2010
2010
Proprotein convertase, subtilisin/kexin type 9 (PCSK9), a key regulator of plasma LDL-cholesterol (LDL-c) and cardiovascular risk… (More)
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2009
2009
OBJECTIVES Proprotein convertase subtilisin kexin type 9 (PCSK9) is a natural inhibitor of the low-density lipoprotein receptor… (More)
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Highly Cited
2009
Highly Cited
2009
The identification and characterization of proprotein convertase subtilisin-like/kexin type 9 (PCSK9) have provided new insights… (More)
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Highly Cited
2008
Highly Cited
2008
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has gained attention as a key regulator of serum low density lipoprotein… (More)
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Highly Cited
2008
Highly Cited
2008
To identify genetic variants influencing plasma lipid concentrations, we first used genotype imputation and meta-analysis to… (More)
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