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Proinsulin to Insulin Ratio Measurement

Known as: PRINSINS, Proinsulin/Insulin Ratio 
The determination of the ratio of the proinsulin compared to insulin present in a sample. The measurement may be expressed as a ratio or percentage.
National Institutes of Health

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3 relations
CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameClinical Data Interchange Standards Consortium Terminology

Papers overview

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2014
2014
Gender differences in non-glycemic responses to improved insulin sensitivity by pioglitazone treatment in patients with type 2 diabetes
Excess cortisol and GH induce insulin resistance, a central feature of type 2 diabetes (T2D). To study whether the insulin… 
2010
2010
Sex differences in the development of diabetes in mice with deleted wolframin (Wfs1) gene.
Wolfram syndrome, caused by mutations in the wolframin (Wfs1) gene, is characterised by juvenile-onset diabetes mellitus… 
2010
2010
Proinsulin levels in patients with pancreatic diabetes are associated with functional changes in insulin secretion rather than pancreatic beta-cell area.
INTRODUCTION Hyperproinsulinaemia has been reported in patients with type 2 diabetes. It is unclear whether this is due to an… 
Highly Cited
2009
Highly Cited
2009
Long-Term Metabolic and Hormonal Effects of Exenatide on Islet Transplant Recipients with Allograft Dysfunction
The initial success of islet transplantation (ITx) is followed by graft dysfunction (GDF) and insulin reintroduction. Exenatide… 
2009
2009
Relation of free and specifically bound leptin to insulin secretion in patients with impaired glucose tolerance (IGT).
Impaired glucose tolerance (IGT) is frequently associated with an increased fat mass and an altered fat distribution. The… 
2008
2008
Development of a feline proinsulin immunoradiometric assay and a feline proinsulin enzyme-linked immunosorbent assay (ELISA): a novel application to examine beta cell function in cats.
Review
2007
Review
2007
For a new paradigm of diabetes.
The main beta cell function is that of pre-proinsulin synthesis and of insulin exocytosis in a regulated manner. After the… 
1999
1999
Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin.
1991
1991
Hyperinsulinaemia in obesity is not accompanied by an increase in serum proinsulin/insulin ratio in groups of human subjects with and without glucose intolerance
SummarySerum proinsulin is disproportionately elevated compared to insulin in Type 2 (non-insulin-dependent) diabetes mellitus… 
1989
1989
Diazoxide-induced long-term hyperglycemia. II. Slackening of proinsulin conversion.
The rate of glucose-stimulated insulin release was found to be increased but that of proinsulin conversion decreased in islets… 
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