Proendothelin (1-38)

Known as: Endothelin-1, Big, Big Endothelin-1, Endothelin, Big 
A 38 amino acid form of endothelin-1 that results from alternative processing of proendothelin-1.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
in Patients With Chronic Heart Failure To the Editor: Berger et al1 conclude that “BNP levels are a strong, independent predictor… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
STUDY OBJECTIVES Primary pulmonary hypertension (PPH) is a rare disease of unknown etiology that is characterized by a poor… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • table 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Matrix metalloproteinase-2 (MMP-2, gelatinase A) and its tissue inhibitor (TIMP-2) are mainly known for their roles in the (patho… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Recent gene targeting studies have revealed unexpected roles for endothelins in the development of neural crest-derived tissues… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Endothelin-converting enzyme 1 (ECE-1) is a membrane-bound metalloprotease that catalyses the conversion of inactive big… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
We sought to examine mechanisms responsible for increased vasoconstriction that occurs during development of nitroglycerin… (More)
  • figure 1
  • table 1
  • table 2
  • figure 3
  • figure 2
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Endothelin-1 (ET-1), a 21-residue vasoactive peptide, is produced in vascular endothelial cells from the 38-residue inactive… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Endothelin (ET) is a 21-residue potent vasoconstrictive peptide produced by vascular endothelial cells and formed from its… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Atherosclerosis and hypertension are more common in men than in women, a difference that may be due, in part, to the actions of… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1990
Highly Cited
1990
PURPOSE Endothelin plays a role in the regulation of vascular tonus. Therefore, it has been hypothesized that increased… (More)
Is this relevant?