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Pristinamycin IIB

Known as: Ostreogrycin G, Virginiamycin IIB 
Pristinamycin IIB is identical to Streptogramin A except that it lacks a double bond at the 2,3-position of the pyrroline moiety of the compound.
National Institutes of Health

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Streptogramin A

Papers overview

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1998
1998
In vitro activity of RPR 106972 alone and in combination with vancomycin, ampicillin, and gentamicin against multidrug-resistant enterococci.
This investigation used checkerboard and time-kill assays to evaluate the in vitro activity of RPR 106972 (45% pristinamycin IB… Expand
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1995
1995
Purification of the two-enzyme system catalyzing the oxidation of the D-proline residue of pristinamycin IIB during the last step of pristinamycin IIA biosynthesis.
High levels of conversion of 14C-labelled pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA) were obtained in vivo in… Expand
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1995
1995
Cloning and analysis of structural genes from Streptomyces pristinaespiralis encoding enzymes involved in the conversion of pristinamycin IIB to pristinamycin IIA (PIIA): PIIA synthase and NADH…
In Streptomyces pristinaespiralis, two enzymes are necessary for conversion of pristinamycin IIB (PIIB) to pristinamycin IIA… Expand
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1995
1995
5 '-phosphate oxidoreductase . PIIA synthase and NADH : riboflavin pristinamycin IIB to pristinamycin IIA ( PIIA ) : enzymes involved in the conversion of Streptomyces pristinaespiralis encoding…
 
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1992
1992
In-vitro and in-vivo synergic activity and fractional inhibitory concentration (FIC) of the components of a semisynthetic streptogramin, RP 59500.
  • D. H. Bouanchaud
  • The Journal of antimicrobial chemotherapy
  • 1992
    • Corpus ID: 11679915
RP 59500 is a new semisynthetic injectable streptogramin antibiotic composed of two compounds which interact synergically, RP… Expand
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