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Precursor Cells, T-Lymphoid

Known as: Precursor, T-Cell, Precursor Cell, T-Lymphoid, Cells, T-Lymphoid Precursor 
Lymphocyte progenitor cells that are restricted in their differentiation potential to the T lymphocyte lineage.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Mutations in the phosphatase and tensin homolog (PTEN) gene leading to PTEN protein deletion and subsequent activation of the… Expand
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Highly Cited
2006
Highly Cited
2006
PU.1 is essential for early stages of mouse T cell development but antagonizes it if expressed constitutively. Two separable… Expand
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Highly Cited
2005
Highly Cited
2005
Signaling through the Notch pathway plays an essential role in inducing T-lineage commitment and promoting the maturation of… Expand
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Highly Cited
2005
Highly Cited
2005
Identification of tumor-associated Ags is a prerequisite for vaccine-based and adoptive immune therapies. Some tumor-associated… Expand
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Highly Cited
2001
Highly Cited
2001
The E2A gene encodes the E47 and E12 basic helix-loop-helix (bHLH) transcription factors. T cell development in E2A-deficient… Expand
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Highly Cited
1999
Highly Cited
1999
Mice mutant for the bHLH gene Hes1, which is known to keep cells in a proliferative state, mostly lack thymus. Transfer of Hes1… Expand
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Highly Cited
1999
Highly Cited
1999
Here, we define the IL-7R-activated signal that promotes survival and proliferation of T cell progenitors and demonstrate that it… Expand
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Highly Cited
1991
Highly Cited
1991
We have investigated the effects of TGF-beta on the in vitro development of different subsets of Th cells and find that addition… Expand
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Highly Cited
1988
Highly Cited
1988
During early fetal development, T cell precursors home from fetal yolk sac and liver to the epithelial thymic rudiment. From… Expand
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Highly Cited
1982
Highly Cited
1982
On the basis of reports that deoxyguanosine is selectively toxic for adult T lymphocytes, the usefulness of this compound in the… Expand
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