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Precursor Cell Lymphoblastic Leukemia Lymphoma

Known as: ALL, Acute Lymphoid Leukemia, Leukemia, Acute Lymphocytic 
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the… 
National Institutes of Health

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10 ML Idarubicin Hydrochloride 1 MG/ML InjectionASPARAGINASEAcute lymphocytic leukemiaAggressive natural killer-cell leukemia
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Acute lymphoblastic leukemia with lymphomatous features

Papers overview

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Highly Cited
2018
Highly Cited
2018
Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia
Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel… 
Highly Cited
2015
Highly Cited
2015
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
Highly Cited
2014
Highly Cited
2014
Chimeric antigen receptor T cells for sustained remissions in leukemia.
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies… 
Highly Cited
2013
Highly Cited
2013
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
Chimeric antigen receptor-modified T cells with specificity for CD19 have shown promise in the treatment of chronic lymphocytic… 
Review
2009
Review
2009
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.
Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society… 
Review
2009
Review
2009
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Highly Cited
2004
Highly Cited
2004
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Very rare cases of human T cell acute lymphoblastic leukemia (T-ALL) harbor chromosomal translocations that involve NOTCH1, a… 
Highly Cited
2001
Highly Cited
2001
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.
BACKGROUND BCR-ABL, a constitutively activated tyrosine kinase, is the product of the Philadelphia chromosome. This enzyme is… 
Highly Cited
1999
Highly Cited
1999
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
Although cancer classification has improved over the past 30 years, there has been no general approach for identifying new cancer… 
Highly Cited
1990
Highly Cited
1990
Graft-versus-leukemia reactions after bone marrow transplantation.
To determine whether graft-versus-leukemia (GVL) reactions are important in preventing leukemia recurrence after bone marrow… 
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