Precursor B-cell lymphoblastic leukemia

Known as: B-cell acute lymphoblastic leukemia, c all, Precursor B-Lymphoblastic Leukemia 
The most frequent type of acute lymphoblastic leukemia. Approximately 75% of cases occur in children under six years of age. This is a good prognosis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05010015019542016

Papers overview

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Highly Cited
2014
Highly Cited
2014
PURPOSE Patients with relapsed or refractory acute lymphoblastic leukemia (ALL) have a dismal prognosis. CD19 is homogenously… (More)
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Highly Cited
2008
Highly Cited
2008
The underlying pathways that lead to relapse in childhood acute lymphoblastic leukemia (ALL) are unknown. To comprehensively… (More)
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Highly Cited
2002
Highly Cited
2002
Immunoglobulin gene rearrangements are used as PCR targets for detection of minimal residual disease (MRD) in acute lymphoblastic… (More)
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Highly Cited
1993
Highly Cited
1993
The expression of B lineage associated genes during early B cell differentiation stages is not firmly established. Using cell… (More)
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1993
1993
Acute lymphoblastic leukemia (ALL) is thought to arise from the clonal expansion of a single transformed precursor cell. However… (More)
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Highly Cited
1991
Highly Cited
1991
OF the various classes of antibodies that B lymphocytes can produce, class M (IgM) is the first to be expressed on the membrane… (More)
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Highly Cited
1991
Highly Cited
1991
The biological functions of the BCL2 gene were investigated in transgenic mice harboring human BCL2 cDNA under the control of an… (More)
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Highly Cited
1986
Highly Cited
1986
Transgenic mice bearing a c-myc oncogene subjugated to the lymphoid-specific immunoglobulin heavy chain enhancer (E mu) develop… (More)
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Highly Cited
1984
Highly Cited
1984
We have developed a general method for introducing cloned genes into mammalian cells that affords substantial benefits over… (More)
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Highly Cited
1982
Highly Cited
1982
The first part of this article discusses the isolation and characterization of several monoclonal antibodies to the B lineage… (More)
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