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Praziquantel

Known as: 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, Prasiquantel, Praziquantel [Chemical/Ingredient] 
A pyrazinoisoquinoline derivative with anthelminthic property. Praziquantel increases the permeability of the tegument of susceptible worms… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently relies on a single drug, praziquantel… Expand
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Highly Cited
2009
Highly Cited
2009
Background The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the… Expand
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Review
2007
Review
2007
The authors discuss the molecular pathogenesis of opisthorchiasis and associated cholangiocarcinogenesis, particularly nitrative… Expand
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Review
2006
Review
2006
Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus Schistosoma. The transmission cycle requires… Expand
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Highly Cited
2005
Highly Cited
2005
Praziquantel has been shown to be highly effective against all known species of Schistosoma infecting humans. Spherical… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryPraziquantel, (2-cyclohexylcarbonyl)-1,2,3,6,7,11b-hexa-hydro-2H pyrazino[2,1a]isoquinolin-4-one, belongs to a new series… Expand
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Highly Cited
2004
Highly Cited
2004
The efficacy of praziquantel against a Puerto Rican strain of Schistosoma mansoni was assessed using both in vivo and in vitro… Expand
Highly Cited
1996
Highly Cited
1996
To determine if resistance/tolerance to the antischistosomal drug praziquantel (PZQ) is appearing in Egyptian villages within the… Expand
Highly Cited
1995
Highly Cited
1995
Schistosoma mansoni was first reported in the area of Richard Toll (Senegal) in 1988 and spread rapidly in the community, after a… Expand
Highly Cited
1994
Highly Cited
1994
Schistosoma mansoni infections in mice were treated with subcurative multiple doses of either praziquantel (PZQ) or oxamniquine… Expand