Praziquantel

Known as: 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-, Prasiquantel, Praziquantel [Chemical/Ingredient] 
A pyrazinoisoquinoline derivative with anthelminthic property. Praziquantel increases the permeability of the tegument of susceptible worms… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Since no vaccine exists against schistosomiasis and the molluscs acting as intermediate hosts are not easy to attack… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the… (More)
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Review
2006
Review
2006
Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus Schistosoma. The transmission cycle requires… (More)
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Highly Cited
2005
Highly Cited
2005
Praziquantel has been shown to be highly effective against all known species of Schistosoma infecting humans. Spherical… (More)
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Highly Cited
2004
Highly Cited
2004
The efficacy of praziquantel against a Puerto Rican strain of Schistosoma mansoni was assessed using both in vivo and in vitro… (More)
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Review
2002
Review
2002
Evidence for resistance to praziquantel (PZQ) in Schistosoma mansoni has been sought in parasites taken from treated, but uncured… (More)
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Review
2001
Review
2001
Neurocysticercosis is the most common helminthic infection of the CNS but its diagnosis remains difficult. Clinical… (More)
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Highly Cited
1996
Highly Cited
1996
To determine if resistance/tolerance to the antischistosomal drug praziquantel (PZQ) is appearing in Egyptian villages within the… (More)
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Highly Cited
1994
Highly Cited
1994
Schistosoma mansoni infections in mice were treated with subcurative multiple doses of either praziquantel (PZQ) or oxamniquine… (More)
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Highly Cited
1977
Highly Cited
1977
Praziquantel, (2-cyclohexylcarbonyl)-1,2,3,6,7,11b-hexa-hydro-2H pyrazino[2,1a]isoquinolin-4-one, belongs to a new series of… (More)
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