Positive Transcriptional Elongation Factor B

Known as: tat Associated Kinase, P-TEFb, tat-Associated Kinase 
A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
By phosphorylating elongation factors and the C-terminal domain of RNA polymerase II, the positive transcription elongation… (More)
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Highly Cited
2012
Highly Cited
2012
The positive transcription elongation factor b (P-TEFb) exists in two forms in cells as follows: an inactive form where the core… (More)
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2011
2011
Promoter-proximal pausing of RNAPII coincides with the formation of the cap structure at the 5' end of pre-mRNA, which is bound… (More)
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Highly Cited
2010
Highly Cited
2010
The Mediator complex allows communication between transcription factors and RNA polymerase II (RNAPII). Cyclin-dependent kinase 8… (More)
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2010
2010
The cellular bromodomain protein Brd4 is a major interacting partner of the papillomavirus (PV) E2 protein. Interaction of E2… (More)
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Highly Cited
2009
Highly Cited
2009
The phosphorylation of the serine 10 at histone H3 has been shown to be important for transcriptional activation. Here, we report… (More)
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2005
2005
The kinase activity of positive transcription elongation factor b (P-TEFb), composed of cyclin-dependent kinase 9 and cyclin T1… (More)
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Highly Cited
2004
Highly Cited
2004
The positive transcription elongation factor b (P-TEFb), comprising CDK9 and cyclin T, stimulates transcription of cellular and… (More)
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Highly Cited
2001
Highly Cited
2001
To stimulate transcriptional elongation of HIV-1 genes, the transactivator Tat recruits the positive transcription elongation… (More)
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Highly Cited
2001
Highly Cited
2001
The CDK9-cyclin T kinase complex, positive transcription elongation factor b (P-TEFb), stimulates the process of elongation of… (More)
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