Porcupine Inhibitor ETC-1922159

Known as: ETC-159, ETC-1922159, PORCN Inhibitor ETC-1922159 
An orally bioavailable inhibitor of the membrane-bound O-acyltransferase (MBOAT) porcupine (PORCN), with potential antineoplastic activity. Upon oral… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2012-2017
02420122017

Papers overview

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Review
2017
Review
2017
Background: The search and wet lab testing of unknown/unexplored/untested biological hypotheses in the form of combinations of… (More)
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Review
2017
Review
2017
Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-differentiation, undergo epigenetic… (More)
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2017
2017
WNT10B belongs to the family of WNT proteins that are implicated in a range of phenomena that are affected by the Wnt signaling… (More)
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2017
2017
  • shriprakash sinhaÆ
  • 2017
DNA repair helps in maintaining the proper and healthy functioning for the cells in the human body. Failure in DNA repair process… (More)
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Review
2017
Review
2017
Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the WNT/β-catenin and WNT/stabilization of… (More)
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2016
2016
Enhanced sensitivity to Wnts is an emerging hallmark of a subset of cancers, defined in part by mutations regulating the… (More)
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2015
2015
SINGAPORE The country’s first publicly funded cancer drug candidate enters phase 1 trials in patients with solid tumors. The drug… (More)
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2012
2012
BACKGROUND Focal Dermal Hypoplasia (FDH) is a genetic disorder characterized by developmental defects in skin, skeleton and… (More)
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